Small Instrument Fleet Technologies
NYU Langone’s Small Instrument Fleet offers researchers access to polymerase chain reaction systems and advanced imaging tools.
Applied Biosystems StepOne Real-Time PCR System
The Applied Biosystems StepOne™ Real-Time PCR System is a 96-well polymerase chain reaction instrument that uses LED three-color optical recording to produce quantitative results. Intuitive data analysis software and advanced instrumentation allow our researchers to pursue genomic projects. Learn more about the Applied Biosystems StepOne™ Real-Time PCR System at Thermo Fisher Scientific’s website.
Bio-Rad CFX96 and CFX384 Touch Real-Time PCR Detection System
The Bio-Rad CFX96 and CFX384 Touch™ Real-Time PCR Detection Systems are six-channel systems featuring advanced optical technology with thermal control. Both deliver dependable data collection and quantitative polymerase chain reaction analysis. More information about the Bio-Rad CFX96 and CFX384 Touch™ is available at the Bio-Rad website.
The Bioruptor®, made by Diagenode, is a sonication system that uniformly processes multiple samples in sealed tubes to avoid cross-contamination. Our researchers use this for shearing chromatin or DNA, cell lysis, and other applications. This instrument is in the Joan and Joel Smilow Research Center, no. 3 cold room. A recirculating water chiller and six-tube adaptor are available to our researchers. Read more about the Bioruptor® at Diagenode’s website.
EVOS FL Color Imaging System
The EVOS® FL Color Imaging System, made by Thermo Fisher Scientific, is an integrated digital microscope featuring four-color fluorescence and transmitted-light applications. This instrument allows researchers to perform high-definition imaging of fluorescent and colorimetrically stained samples. Learn more about the EVOS® FL Color Imaging System at Thermo Fisher Scientific’s website.
GE Typhoon Trio
The GE Typhoon Trio™ is an imaging system that uses three lasers to allow excitation and visualization of a wide wavelength range. Instrument applications can be used for analysis of fluorescent-stained protein gels, Western blots, and nucleic acid stains, as well as two-dimensional difference gel electrophoresis. Researchers use GE’s ImageQuant TL Software for data analysis. For more information about GE’s Typhoon Trio™, please see the user guide.
GenePix 4000B Microarray Scanner
The GenePix® 4000B Microarray Scanner includes advanced data analysis with GenePix® Pro Microarray Image Analysis Software and Acuity® Microarray Informatics Software. Researchers assess nucleic acid, protein, tissue, and cell microarrays. This imaging system uses two wavelengths to reduce scanning time and increase accuracy. Read more about the GenePix® 4000B Microarray Scanner at Molecular Devices’ website.
LI-COR Odyssey Fc Imaging System
The Odyssey® Fc Imaging System, made by LI-COR, uses two channel near-infrared fluorescence to produce accurate digital images of DNA gels and Western blots. Researchers can simplify chemiluminescent imaging with limited instrument adjustments or multiple exposures. Image Studio™ software provides rapid analysis. More information about the Odyssey® Fc Imaging System is available on LI-COR’s website.
LI-COR Odyssey Infrared Imaging System
The LI-COR Odyssey® Infrared Imaging System uses near-infrared fluorescence to provide a wide linear dynamic range and better sensitivity than chemiluminescence. The system can provide Western blot analysis, DNA gels, protein arrays, and many other applications.
FlexStation 3 Multi-Mode Microplate Reader
The FlexStation® 3 Multi-Mode Microplate Reader, made by Molecular Devices, is a benchtop device with numerous biochemical- and cell-based applications. The instrument can be used for fluorescence intensity, fluorescence polarization, time-resolved fluorescence, and luminescence assays. It uses SoftMax® Pro 7 Data Acquisition and Analysis Software.
NanoDrop 8000 UV-Vis Spectrophotometer
The NanoDrop™ 8000 UV-Vis Spectrophotometer, made by Thermo Fisher Scientific, enables researchers to measure up to 8 microvolume protein and nucleic acid samples simultaneously and to evaluate the purity of samples as small as 1 μL. The NanoDrop™ 8000 comes with intuitive software for data analysis. Learn more about the NanoDrop™ 8000 UV-Vis Spectrophotometer at Thermo Fisher Scientific’s website.
Agilent 2100 Bioanalyzer
The Agilent 2100 Bioanalyzer provides sizing, quantitation, and quality control of total RNA, messenger RNA, and DNA on a chip format. For more information, see NYU Langone’s Translational Research Laboratory.