Wang Lab Publications

Read the latest papers published by investigators in NYU Langone’s Wang Lab.

Selected Publications

Substrate translocation and inhibition in human dicarboxylate transporter NaDC3

Li, Yan; Song, Jinmei; Mikusevic, Vedrana; Marden, Jennifer J; Becerril, Alissa; Kuang, Huihui; Wang, Bing; Rice, William J; Mindell, Joseph A; Wang, Da-Neng

Nature structural & molecular biology. 2025 Mar ; 32:502-512

A fiducial-assisted strategy compatible with resolving small MFS transporter structures in multiple conformations using cryo-EM

Xie, Pujun; Li, Yan; Lamon, Gaëlle; Kuang, Huihui; Wang, Da-Neng; Traaseth, Nathaniel J

Nature communications. 2025 Jan 02; 16:7

Proton-coupled transport mechanism of the efflux pump NorA

Li, Jianping; Li, Yan; Koide, Akiko; Kuang, Huihui; Torres, Victor J; Koide, Shohei; Wang, Da-Neng; Traaseth, Nathaniel J

Nature communications. 2024 May 27; 15:4494

Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus

Brawley, Douglas N; Sauer, David B; Li, Jianping; Zheng, Xuhui; Koide, Akiko; Jedhe, Ganesh S; Suwatthee, Tiffany; Song, Jinmei; Liu, Zheng; Arora, Paramjit S; Koide, Shohei; Torres, Victor J; Wang, Da-Neng; Traaseth, Nathaniel J

Nature chemical biology. 2022 Jul ; 18:706-712

Structural basis of ion - substrate coupling in the Na⁺-dependent dicarboxylate transporter VcINDY

Sauer, David B; Marden, Jennifer J; Sudar, Joseph C; Song, Jinmei; Mulligan, Christopher; Wang, Da-Neng

Nature communications. 2022 May 12; 13:2644

The ups and downs of elevator-type di-/tricarboxylate membrane transporters

Sauer, David B; Wang, Bing; Sudar, Joseph C; Song, Jinmei; Marden, Jennifer; Rice, William J; Wang, Da-Neng

FEBS journal. 2022 Mar ; 289:1515-1523

Structure and inhibition mechanism of the human citrate transporter NaCT

Sauer, David B; Song, Jinmei; Wang, Bing; Hilton, Jacob K; Karpowich, Nathan K; Mindell, Joseph A; Rice, William J; Wang, Da-Neng

Nature. 2021 Mar ; 591:157-161

Structural basis for the reaction cycle of DASS dicarboxylate transporters

Sauer, David B; Trebesch, Noah; Marden, Jennifer J; Cocco, Nicolette; Song, Jinmei; Koide, Akiko; Koide, Shohei; Tajkhorshid, Emad; Wang, Da-Neng

eLife. 2020 Sep 01; 9:

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Wang Lab Publications | NYU Langone Health