Establishing test-retest reliability of swallowing pressures collected with High Resolution Pharyngeal Manometry (HRPM)
We are seeking healthy older adults (65+) to participate in two study visits to measuring swallowing function using two different tests at the same time (swallowing pressures and swallowing X-ray). Participants will have a catheter passed through their nose and swallow barium. Study visits will last one hour each and occur two weeks apart. Each participant will be offered $100 upon completion of each of the two assessment visits for $200 total on study completion.
Evaluating a Noise Reduction Algorithm with Cochlear Implant Users
In this study, a noise reduction algorithm will be implemented in various listening situations to evaluate its effectiveness in improving speech understanding for 180 cochlear implant users ages 12 and older.
Evaluation of [13N]- Ammonia- and [18F]-FDG-PET/cMRI for Cardiac Sarcoidosis
The purpose of this study is to evaluate the accuracy and clinical significance or benefit of using a combined [13N]- Ammonia- and [18F]-FDG-PET/cMRI for evaluation of cardiac sarcoidosis and to assess the biomarkers associated with the disease. Positron Emission Tomography, commonly referred to as PET involves the use of injected compounds known as radiotracers (like [13N]-Ammonia and [18F] FDG) to make images that give us information about conditions in your body. In contrast, Magnetic Resonance Imaging or MRI uses a magnet instead of radiation to visualize the inside of your body. Contrast (dye) is commonly injected to enhance the clarity of the images.
Evaluation of cardiac function with cardio-respiratory synchronized MRI
The purpose of the proposed study is to evaluate of newer methods of performing cardiovascular Magnetic Resosnance Imaging (MRI) that allows us to investigate the effects of breathing on cardiac function. We have been developing a different novel approach to performing cardiovascular MRI (CMR), that relies on continuous acquisition of data with a different means of creating effective synchronization with both the cardiac and respiratory cycles during the image reconstruction. This new approach has been very promising in our initial applications to imaging of patients undergoing routine CMR. We would now like to evaluate its potential utility for evaluation of patients where there may be alteration of the normal LV/RV interactions. You/your child are being asked to participate in this study because it has been determined that you/your child have: Cardiovascular or respiratory disease that may affect the function of your/your child’s heart in ways that can be revealed with this new CMR method, and thus can help us to learn what motion patterns are expected to be seen with this new imaging method, or no known cardiovascular or respiratory disease.
EVALUATION OF FREQUENCY ALLOCATION TABLES FOR RECENTLY IMPLANTED SINGLE-SIDED DEAF COCHLEAR IMPLANT USERS
This observational study will examine cochlear implant (CI) patients with single-sided deafness (SSD) who receive non-default frequency allocation tables (FATs) after initial stimulation to determine how it affects performance with the device. Behavioral tests of hearing will be measured longitudinally, and include measures of sound quality, listening effort, device satisfaction, and speech perception abilities.
Evaluation of HFCWO using The Vest System for Treatment of Non-Cystic Fibrosis Bronchiectasis in the home setting
The study will be a non-blinded prospective Randomized Control Trial (RCT) pilot study with subjects requiring airway clearance therapy randomized to Oscillating Positive Expiratory Pressure (OPEP) therapy as the control group and High Frequency Chest Wall Oscillation (HFCWO) therapy as the intervention group. The objective is to evaluate the use of The Vest® System to treat Non-Cystic Fibrosis Bronchiectasis (NCFBE) patients in the home setting with the primary endpoint of frequency of acute exacerbations of bronchiectasis.
Evaluation of the Safety and Effectiveness of the CereVasc eShunt System in the Treatment of Normal Pressure Hydrocephalus
This study is evaluating the eShunt System for the treatment of patients with normal pressure hydrocephalus. The treatment is intended to reduce disability due to symptoms including one or more of gait disturbance, cognitive dysfunction and urinary incontinence.
EVEREST-1: A Phase 1/2 Study to Evaluate the Safety and Efficacy of A2B530 an Autologous Logic-gated Tmod Chimeric Antigen Receptor T Cell (CAR T) in Heterozygous HLA-A*02 Adult Subjects with Recurrent Unresectable Locally Advanced or Metastatic Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression
This is a study to see if a new treatment called A2B530 is safe and effective for people with certain types of cancer that have not been able to be removed with surgery. The patient must have a specific HLA type known as HLA-A*02. A2B530 is a type of therapy called CAR T cell therapy. It is a form of engineered immune cells derived from a patient and is designed to target cancer cells. The study will be done in two parts. In the first part, a small group of people will receive different amounts of A2B530 in order to decide,what the best dose of the drug will be. In the second part, additional people will get the best dose of A2B530 discovered from part 1 and evaluate how well this dose works amongst a wider group of people.
Examining the Impact of Family Connectors
The purpose of this study is to understand the impact of Family Connectors, a peer-to-peer support and education program for family members who have participated in OnTrackNY, a treatment program for adolescents and young adults.
Executive Administration & Musculoskeletal Advisory Board at NYU Langone Orthopedic Hospital | NYU Langone Health
NYU Langone Orthopedic Hospital is led by an executive administration and musculoskeletal advisory board.