Vaccine Center Research | NYU Langone Health

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Vaccine Center Vaccine Center Research

Vaccine Center Research

Researchers at NYU Langone’s Vaccine Center use state-of-the-art methods to tackle complex problems in vaccine research. Our basic science and clinical research studies are designed to produce innovative new vaccines and devise ways to make their delivery painless and effective.

In response to the COVID-19 pandemic, we are leaders in the development of effective vaccines and treatments to combat infection with SARS-CoV-2, the virus that causes COVID-19. Our COVID-19 clinical studies are detailed below, and we also have an active COVID-19 vaccine and treatment research program.

In addition to COVID-19, communities around the world are devastated by influenza, tuberculosis, malaria, and HIV/AIDS, conditions that are resistant to many existing drugs and targeted vaccines. Our challenge is to find new ways to combat these diseases and to identify safe, broadly effective vaccines that can make a powerful difference in global health.

We also focus on developing novel vaccines for nonviral and nonmicrobial illnesses including Alzheimer’s disease, autoimmune diseases, opioid use disorder, cancers, and other chronic conditions.

Beyond vaccine development, we lead research projects to develop new diagnostics and predictive markers to help providers detect disease early and predict the effectiveness of inoculation.

Active Clinical Studies

The Vaccine Center has ongoing studies that support future vaccine trials and studies of the human immune system and infectious diseases. This research builds on prior studies of the human immune response to infections and offers deeper insight into the complexity of these responses. It also holds possibilities for the development of rapid responses to emerging infectious threats.

If you are interested in enrolling, please email us at nyuvaccinecenter@nyulangone.org.

A Study of SARS-CoV-2 Infection and Potential Transmission in Individuals Immunized With Moderna COVID-19 Vaccine

Enrolling at the NYC Health + Hospitals/Bellevue and NYU Langone Hospital—Long Island satellite sites of the Vaccine Center.

See full clinical trial information.

Delayed Heterologous SARS-CoV-2 Vaccine Dosing (Boost) After Receipt of EUA Vaccines

Enrolling at the NYC Health + Hospitals/Bellevue and NYU Langone Hospital—Long Island satellite sites of the Vaccine Center.

See full clinical trial information.

Phase 3 Randomized Double-Blind Placebo-Controlled Study Assessing the Efficacy and Safety of Anti-Spike SARS-CoV-2 Monoclonal Antibodies in Preventing SARS-CoV-2 Infection in Household Contacts of Individuals Infected with SARS-CoV-2

See full clinical trial information.

Phase 3 Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults

See full clinical trial information.

Phase 1/2 Placebo-Controlled Randomized Observer-Blind Dose-Finding Study to Describe the Safety Tolerability Immunogenicity and Potential Efficacy of SARS-CoV-2 RNA Vaccine Candidates Against COVID-19 in Healthy Adults

See full clinical trial information.

Multicenter Adaptive Randomized Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for the Treatment of COVID-19 in Hospitalized Adults

See full clinical trial information.

Phlebotomy of Healthy Adults for the Purpose of Evaluation and Validation of Immune Response and Microbiology Assays

See full clinical trial information.

Specimen Collection for Infectious Diseases with Public Health Importance

See full clinical trial information.

Randomized Phase 2 Study of VE303 for Prevention of Recurrent Clostridium Difficile Infection (CONSORTIUM)

See full clinical trial information.

Our Research Facilities

The Vaccine Center has basic research and clinical spaces in multiple NYU Langone research facilities.

Vaccine Center labs and clinical spaces are located in the following facilities: