NYU Langone’s Vaccine Center leads a range of ongoing clinical studies to explore the safety and effectiveness of new vaccines or therapeutics.

Active Clinical Studies — Enrolling

Escherichia coli (E. coli) Study

A Phase 1, randomized, observer-blind study to evaluate the safety, and tolerability, of FimH modRNA and O25b conjugate (with or without adjuvant) vaccine against E coli in healthy adults.

Pneumococcal Disease Study

Streptococcus pneumoniae is a common type of bacteria that can cause a wide variety of infections, including serious infections like pneumonia. This study evaluates if an investigational Pneumoccocal vaccine is safe and can help the body produce an immune response against Pneumoccocal disease.

HIV prevention Study

The purpose of this study is to evaluate the effect of addressing health-related social needs for people taking long-acting injectable HIV prevention medication (LAI-PrEP).

Mpox Immunity Study

The purpose of this study is to measure immunity against mpox in people who have been have been infected with mpox.

Flu (Influenza) Study in Lung Transplant Recipient

The purpose of this research study is to learn about how lung transplant recipients respond to different flu vaccines.

Measles Immunity study

The purpose of this study is to develop a new assay for the measurement of measles-specific immunity. We are only enrolling people who have recently recovered from measles (recently convalescent).

If you have questions about clinical trials and participating in a study at the Vaccine Center, please email us at nyuvaccinecenter@nyulangone.org

Active Clinical Studies — Closed to Enrollment

The following clinical studies are active at our center but are not enrolling participants at this time. Explore our enrolling studies to learn more about how you can participate in a clinical study with us. You can also view a list of past clinical studies to learn more about the scope of our work.

Active Clinical Studies—Enrollment Closed

The following clinical studies are active at our center but are not enrolling participants at this time. Explore our enrolling studies to learn more about how you can participate in a clinical study with us. You can also view a list of past clinical studies to learn more about the scope of our work.

RSV (Respiratory Syncytial Virus) Studies

Study on Safety and Immunology of Maternal and Infant RSV Vaccination Approaches.

Study on Safety and Tolerability of Investigational modRNA RSV Vaccine in Healthy Adults.

Study on Safety and Immunogenicity of RSV Vaccine in Adults with Chronic Health Conditions or Immunocompromise.

Clostridioides difficile (C. diff) Study

Study on Safety, Tolerability, and Immunogenicity of Clostridioides difficile Vaccine with Novel Adjuvants in Healthy Adults.

HIV Study

Study on Safety and Efficacy of Weekly Oral Regimen vs. Standard Treatment in Virologically Suppressed HIV-1 Patients.

Mpox Study

New York City Observational Study of Mpox Immunity: NYC OSMI

Shingles Study

Study on Safety and Efficacy of New mRNA Shingles Vaccine Compared to Existing Vaccine

Flu (Influenza) Studies

The Stop Flu NYU Cohort Study (part of the Center for Research on Influenza Pathogenesis and Transmission, CRIPT)

Yellow Fever Study

Controlled Study Comparing the Immune Response and Safety of a Research Yellow Fever Vaccine Candidate to a Licensed Yellow Fever Vaccine for Adults

Lyme Disease Study

Study on New Pfizer Lyme Disease Vaccine in Pediatric Volunteers