RELATIONSHIP BETWEEN SYNOVIAL FLUID BIOMARKERS IN ACL RECONSTRUCTED PATIENTS AND PROGRESSION OF OSTEOARTHRITIS
We will perform a cross-sectional study on 25 patients undergoing isolated ACL reconstruction (intact menisci and articular cartilage). We have previously obtained samples of synovial fluid from both knees under a previously accepted IRB (IRB: i15-00929). At 5 years post-operatively we will perform clinical MRI on both knees with measurement of cartilage morphology, and novel imaging of articular cartilage to assess collagen and proteoglycan (PG) content. We will test our primary hypothesis that the time of surgery concentration of a panel of synovial biomarkers recently described in our laboratories will correlate with the extent of cartilage loss occurring post-operatively. Primary ObjectiveTo create a biomarker-model that can predict the development of cartilage loss and post-traumatic osteoarthritis at the relatively short term 5-year follow-up timepoint through analysis of synovial fluid samples collected at the time of surgery. Secondary ObjectiveTo compare synovial fluid biomarker profiles between patients who demonstrate evidence of accelerated articular cartilage loss following ACL reconstruction using advanced MRI based imaging techniques to patients whose articular cartilage remains intact post-operatively.
Relationship between the ocular microbiome and pseudoexfoliation syndrome/glaucoma and cataracts
Observational study to determine the microbiome structure of the eye, mouth, and skin of subjects with pseudo exfoliation syndrome, pseudoexfoliation glaucoma, and cataracts before and after cataract and/or glaucoma surgery; and compare it to the microbiome of healthy controls.
Religious Services, Items & Meal Requests | NYU Langone Health
Chaplains, imams, priests, and rabbis at NYU Langone can perform religious services or supply sacred texts to patients during a hospital stay.
Remote Monitoring of Cardiac Devices | NYU Langone Health
The cardiac device team at NYU Langone’s Heart Rhythm Center provides remote monitoring of implantable cardiac devices.
Renal Artery Stenosis | NYU Langone Health
NYU Langone vascular specialists manage renal artery stenosis, a narrowing of the arteries that lead to the kidneys.
Renal Transplant Equity Through Partnership and Structural Transformation
This is a formative study evaluating the effect of community health workers and provider education on kidney transplant waitlisting compared to usual care. In this study, the study team will conduct in depth individual interviews and/or group focus groups with individuals involved in all aspects of the kidney transplantation process to have them share their feelings, perceptions, and knowledge on the kidney transplantation process. The study team will use information learned from these sessions to better inform our subsequent intervention and provider education materials.
Renal Tubular Disorders in Children | NYU Langone Health
NYU Langone doctors are experts at diagnosing and treating children with renal tubular disorders, which can cause kidney and growth problems.
Repair Surgery for Distal Biceps Tendon Rupture | NYU Langone Health
NYU Langone’s highly trained orthopedic surgeons are experts at performing repair procedures for a distal biceps tendon rupture.
Repeat Cesarean Delivery | NYU Langone Health
If NYU Langone specialists determine that a vaginal birth after cesarean, or VBAC, cannot progress safely, they perform surgery immediately.
Reproductive & Sexual Health | NYU Langone Health
NYU Langone doctors provide personalized treatment for reproductive and sexual health conditions in men and women.