Retinoblastoma in Children | NYU Langone Health
Specialists at Hassenfeld Children’s Hospital at NYU Langone diagnose and treat children with retinoblastoma, a rare eye cancer.
Return to Work Program | NYU Langone Health
NYU Langone Occupational and Industrial Orthopedic Center offers a work conditioning program called the return to work program to help people resume their jobs.
Reuniting Heart with Home | NYU Langone Health
At NYU Langone we provide care for the tiniest of hearts. Learn more about our pediatric cardiology and heart surgery program, which is No. 1 in New York.
Reverse End to Side Transfer for Severe Cubital Tunnel Syndrome
This prospective study will investigate outcomes in patients with severe cubital tunnel syndrome between patients that undergo reverse end to side (RETS) transfer and patients that undergo decompression and neurolysis.
Reversing Diabetic Peripheral Neuropathy Through Exercise
This cross-over design study proposes an innovative multinuclear MRI approach to gain mechanistic insight into the exercise-associated adaptations in lower leg muscle function and peripheral nerve integrity of patients with diabetic peripheral neuropathy (DPN). Currently, there are no therapies to prevent or reverse the progress of DPN. Our team is uniquely positioned to use novel multinuclear MRI technology to understand how exercise affects skeletal muscle and peripheral nerve integrity and function in patients with DPN. We will prescribe a 4-week non-exercise phase followed by a 10-week exercise program (with both aerobic and strengthening components) to 40 DPN patients who will receive personal supervision from health professionals.
Revisional Surgery | NYU Langone Health
Surgeons at NYU Langone’s Weight Management Program have vast experience in performing revisional surgeries after primary weight loss surgery.
Rheumatoid Arthritis | NYU Langone Health
NYU Langone doctors manage rheumatoid arthritis, a condition that often causes joint pain and swelling, most commonly in the hands and feet.
Rheumatology SAMPLE (Specimen And Matched Phenotype Linked Evaluation) Registry and Biorepository
In this research proposal, we will develop a clinical registry containing information related to the patient’s ethnicity, race, gender, age, medications, specific disease or state of health and biorepository (tissue bank collection of blood samples, urine, and feces) of patients with autoimmune and rheumatic diseases, including but not limited to rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), psoriatic arthritis, Sjogren’s syndrome, gout, anti-phospholipid syndrome (aPLS), Behςet’s Disease and other forms of inflammatory arthritis. In addition, we will develop a biorepository for healthy individuals without autoimmune rheumatic diseases, as well as for healthy individuals who may be related to a patient with an autoimmune and rheumatic disease. The scientific objective is to understand what factors contribute to the risk of getting an autoimmune and/or rheumatic disease, what factors make the disease worse, what factors relate to whether a therapy helps improve disease, and what factors lead to health problems other than the specific disease. For this purpose, electronic medical records will be reviewed and subjects will complete disease-targeted questionnaires (listed in study design) that are part of the standard of care for management of the specific rheumatic disease. A biorepository (tissue bank) will be developed for the storage of genetic material (DNA), blood cell RNA, plasma, serum, feces, urine, and lymphoblastoid cell lines (LCLs) from patients with these autoimmune and/or rheumatic diseases and healthy individuals. These materials will be used in basic science investigations of the pathogenesis of disease, and will also be used in translational research projects that will correlate the clinical characteristics and responses to treatment at NYU. Specifically, examples of the types of studies to be done include but are not limited to: 1) targeted genetic assays for single nucleotide polymorphisms (SNPs) of candidate genes (e.g. TNF, IL6, IL23), as well as genome-wide platforms for empiric-based analyses using genome wide association study (GWAS) approaches; 2) transcript-based assays of candidate gene expression (e.g. interferon-related genes) as well as empiric-based broader approaches (full transcriptome); 3) serum and plasma assays for specific autoantibodies (e.g. citrullinated peptide antibodies), secreted proteins (e.g. cytokines) that can be measured using proteomic assays (e.g. ELISA and other techniques); urine for markers of tissue/organ catabolism/damage; 4) stool samples for 16S DNA bacterial DNA sequence and whole-genome shotgun-sequence determinations for characterization of the microbiome (3) (4-6) (7) (8), and 5) discovery of Quantitative Trait Loci (eQTLs) of LCLs. Repeat sampling and clinical data collection will be needed. These studies may or may not affect treatment or determine prognosis for an individual subject. However, a potential benefit of this research includes the possibility of finding a marker that predicts a response to therapy representing information which may be useful to future patients.
Rheumatology Services | NYU Langone Health
Doctors at NYU Langone Orthopedic Center specialize in arthritis and diseases related to joints, soft tissue, and autoimmunity.
Risk factors for sudden unexplained death in epilepsy (SUDEP)
The registry is a database created to document SUDEP (sudden unexplained death in epilepsy patients) cases. Our goals are to increase knowledge and awareness about epilepsy related mortality. We are interested in obtaining clinical records and DNA and/or brain tissue - on suspected SUDEP cases.