The Highest Standard of Care | NYU Langone Health
At NYU Langone we provide the highest standard of care, and every day we strive to set those standards even higher. See our care in action.
The HistoSonics Edison System for treatment of primary solid renal tumors using histotripsy (#HOPE4KIDNEY US)
This study is testing the HistoSonics Edison System for treating kidney tumors using histotripsy (involves using focused ultrasound beams from outside the body to create tiny bubbles that burst and break apart cancer tissue, turning it into small pieces without the need for surgery or cutting). It's designed to confirm the HistoSonics Edison System's effectiveness in treating kidney tumors before it becomes available in the market. The target population includes patients aged 22 or older with a single kidney tumor up to 3cm in size. The trial is expected to last about 7 years, including an enrollment phase of around 18 months and follow-up for up to five years after the procedure. The trial is designed this way because there's limited data on kidney tumor treatments, and this approach helps ensure patient safety while evaluating the new treatment's effectiveness.
The Janus Rectal Cancer Trial: A Randomized Phase II Trial Testing the Efficacy of Triplet Versus Doublet Chemotherapy to Achieve Clinical Complete Response in Patients with Locally Advanced Rectal Cancer
This study will focus on improving chemotherapy response rates in bothprimary and metastatic rectal and colorectal cancer. In this study, patients willbe divided into two groups to receive different treatments. The first group willbe treated with LCRT (locally confined radiation therapy) followed byconsolidation FOLFOX (a combination of the chemotherapy drugs Oxaliplatin,5-FU, and Leucovorin). The second group will receive LCRT followed byconsolidated chemotherapy with mFOLFIRINOX, which is a more intensechemotherapy regimen. This approach using stronger chemotherapy hasbeen found to improve the response rates in both primary and metastatic rectal and colorectal cancer.
The Lifestyle Intervention in Fibroid Elimination Program (LIFE)
This prospective cohort pilot study will enroll asymptomatic, post-surgical patients who underwent a laparoscopic, open, robotic myomectomy, or other procedure ie Sonata, Accessa for fibroid removal. Patients will be offered enrollment into a lifestyle, nutrition, supplement, and exercise program to assess whether this program is acceptable and feasible for patients. Surveys will be collected at 3-6 month intervals. Ultimately, we hope to better understand if LIFE can modify fibroid recurrence.
The MAINSTAY study: Mechanisms of rAcial dIfferences in the relatioNship between Obstructive Sleep Apnea and in vivo Tau deposition in the context of AmYloid burden
This research study is being done to collect information about obstructive sleep apnea (OSA) as a potential risk factor that may increase Alzheimer’s disease (AD) burden, particularly in African-Americans, and understand racial differences in markers of AD.
The MENTOR Wellness Program for Individuals with Traumatic Brain Injury
The purpose of this research study is to test how helpful a virtual wellness program is for individuals with traumatic brain injury (TBI) who had the injury at least one year ago. This program, called the Mindfulness, Exercise, Nutrition to Optimize Recovery (MENTOR), was designed for people with physical disabilities and we want to understand how effective it is for individuals with TBI. During study, you will be asked to participate in an 8-week online group wellness intervention that meets up to 5 times a week from the comfort of your home. You will also be asked to complete up to four surveys throughout the course of the study. All study activities will be virtual.
The Natural History of Partial Ligamentous Tears in the Wrist
The purpose of this study is to better understand common injuries in the wrist. Patients who fall or otherwise injure their hand or wrist can injure ligaments – the tough connections that help stabilize bones in the wrist. Two of these important ligaments and stabilizers are called the Scapholunate Ligament (SLL) and the Triangular Fibrocartilage Complex (TFCC). The data to be collected will provide important information on how these common injuries heal.
THE NEPHROTIC SYNDROME STUDY NETWORK (NEPTUNE)
Childhood onset nephrotic syndrome is a condition which affects the kidneys causing them to leak protein from the blood into the urine. Nephrotic syndrome is a disease that can improve (remission) and worsen (relapse) at different times throughout childhood. By collecting health information and laboratory samples, The goal of this research is to learn more about these kidney diseases and find better ways to prevent and treat people with nephrotic syndrome. New knowledge will be shared with researchers and the public.
The New York City Study of FeRtility and Environmental Exposures (NYC FREE)
NYC FREE is a fertilitiy study that will enroll people of reproductive age who live or work in New York City and have the potential to become pregnant in the future, as well as partners of these individuals. The overall aim of this project is to create a biobank that will facilitate future studies on the relation of environmental and lifestyle factors with reproductive health and human fecundity. Please visit https://www.nycfree.org/ to learn more about this study.
THE NEW YORK MOVEMENT DISORDER (NYMD) STUDY
The purpose of this study is to advance our understanding of the changes that cause brain disorders, such as movement disorders. Currently, treatment strategies to address movement disorders are largely aimed at symptoms, but not the underlying cause of the disease. The goal of this study is to increase our knowledge of what causes these diseases and use this information to help find ways to diagnose and treat them. This study is looking to enroll subjects who have been diagnosed with a nervous system disorder.