Immunotherapy & Targeted Therapies for Colorectal Cancer | NYU Langone Health
Doctors at NYU Langone’s Perlmutter Cancer Center may prescribe immunotherapy or targeted therapies to treat colorectal cancer.
Immunotherapy for Glioma & Astrocytoma | NYU Langone Health
Doctors at NYU Langone’s Perlmutter Cancer Center may use immunotherapy to prevent glioma or astrocytoma tumors from growing or spreading.
Immunotherapy for Myasthenia Gravis | NYU Langone Health
NYU Langone specialists may administer a protein called immunoglobulin to treat severe myasthenia gravis.
Immunotherapy for Vasculitis | NYU Langone Health
Langone doctors may prescribe intravenous immunoglobulin therapy for people with more serious forms of vasculitis.
Impact of A Structured Anxiety Reduction Program on Anxiety in Patients Who Are Discharged to Home Following an Acute Stroke in an Academic Medical Center
The purpose of this research study is to determine if participating in a structured anxiety reduction program helps to decrease your experience of anxiety after suffering an acute stroke. The structured anxiety reduction program that will be offered to you is from material that is available at NYU Langone Health regularly. This research study is being done to collect your thoughts and reactions to an anxiety reduction program offered to you made up of components offered by NYU Langone health. We will do this through surveys. The surveys will include some of your personal health information and your baseline anxiety followed by your response after 3 months to the anxiety reduction program and your evaluation of the program.
Impact of time restricted feeding in obese subjects undergoing a low-calorie diet
The impact of circadian rhythms appear to impact various biologic mechanisms including sleep, nutrition, and physical activity. We wish to understand the impact of timing of food consumption and how it may affect weight loss. Participants in the study will be undergoing a low calorie diet, and we will attempt to vary the times at which participants will eat. We will examine differences in rates of weight loss over the course of two, four and eight weeks. This will be an initial pilot study in an attempt to see if there is more effective weight loss with time restricted feeding.
Impact of Weight Loss in Patients with Hypertrophic Cardiomyopathy
This is an observational imaging study to evaluate the cardiac effects of weight loss in obese patients with a BMI >=30 with a confirmed diagnosis of hypertrophic cardiomyopathy. The sample size will be 120 patients. Based on the clinical evaluation of the NYU Langone Health Weight Management Program and on patient preference, patients will be offered either bariatric surgery or a diet and exercise regimen. Patient management before, during, and after weight loss intervention(s), including subsequent follow-up, will be in accordance to standard of care. Patients will have echocardiographic and quantitative radiographic imaging either by Cardiac MRI or ECG-Synchronized cardiac CT angiogram of the chest no more than 3 months before and again 18 months after their patient-chosen weight loss program. MRI is the preferred method of radiographic imaging while CT will be reserved only for patients who have a pacemaker or implanted cardiac defibrillator. Patients who do not complete their chosen weight loss program or those who do not lose weight by the End of Study visit will still undergo final research imaging procedures for comparison analysis.
IMPact on Revascularization Outcomes of intraVascular ultrasound guided treatment of complex lesions and Economic impact (IMPROVE)
The study is being done to evaluate the impact of treating complex blockages in the coronary arteries of subjects undergoing percutaneous coronary intervention (PCI) with the imaging guidance of Intravascular Ultrasound (called IVUS, which is an imaging method that uses ultrasonic waves to see your vessel wall from the inside of the artery). The study will assess whether the use of IVUS improves subjects' clinical outcomes at 1 year following this PCI procedure. These subjects will be compared to subjects who did not undergo such IVUS imaging guidance during their PCI procedures.
Impella -Supported PCI in High-Risk Patients with Complex Coronary Artery Disease and Reduced Left Ventricular Function: The PROTECT IV Trial
The primary objective of the PROTECT IV Trial is to demonstrate the superiority of percutaneous coronary intervention (PCI) performed with Impella mechanical circulatory support (MCS; Impella CP®, Impella CP® with SmartAssist® or Impella 2.5® devices) compared with PCI without Impella in high-risk patients with reduced left ventricular ejection fraction undergoing percutaneous intervention of complex coronary artery disease (CAD). The principal hypothesis is that by providing effective hemodynamic support in high-risk patients with reduced left ventricular systolicfunction and complex CAD undergoing high-risk PCI, Impella mechanical circulatory support will facilitate a safer procedure with higher rates of optimal and complete revascularization, which will lead to improved event-free survival, quality of life (QoL) and functional outcomes at 3-year followup.
Implantable Cardioverter Defibrillator for Ventricular Arrhythmias | NYU Langone Health
NYU Langone doctors use implanted cardioverter defibrillators to manage the symptoms of ventricular arrhythmias.