Genome Technology Center Featured Publications

Our staff members and collaborators frequently publish their research in leading peer-reviewed publications. Here is a selection of their recent accomplishments.

Selected Publications

Profiling hippocampal neuronal populations reveals unique gene expression mosaics reflective of connectivity-based degeneration in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease

Alldred, Melissa J; Ibrahim, Kyrillos W; Pidikiti, Harshitha; Lee, Sang Han; Heguy, Adriana; Chiosis, Gabriela; Mufson, Elliott J; Stutzmann, Grace E; Ginsberg, Stephen D

Frontiers in molecular neuroscience. 2025 Mar ; 18:1546375

Digital spatial profiling to predict recurrence in grade 3 stage I lung adenocarcinoma

Chang, Stephanie H; Mezzano-Robinson, Valeria; Zhou, Hua; Moreira, Andre; Pillai, Raymond; Ramaswami, Sitharam; Loomis, Cynthia; Heguy, Adriana; Tsirigos, Aristotelis; Pass, Harvey I

Journal of thoracic & cardiovascular surgery. 2024 Sep ; 168:648-657.e8

Cellular dynamics in pig-to-human kidney xenotransplantation

Pan, Wanqing; Zhang, Weimin; Zheng, Binghan; Camellato, Brendan R; Stern, Jeffrey; Lin, Ziyan; Khodadadi-Jamayran, Alireza; Kim, Jacqueline; Sommer, Philip; Khalil, Karen; Weldon, Elaina; Bai, Jiangshan; Zhu, Yinan; Meyn, Peter; Heguy, Adriana; Mangiola, Massimo; Griesemer, Adam; Keating, Brendan J; Montgomery, Robert A; Xia, Bo; Boeke, Jef D

Med (New York, N.Y.). 2024 Aug 09; 5:1016-1029.e4

Analysis of microisolated frontal cortex excitatory layer III and V pyramidal neurons reveals a neurodegenerative phenotype in individuals with Down syndrome

Alldred, Melissa J; Pidikiti, Harshitha; Ibrahim, Kyrillos W; Lee, Sang Han; Heguy, Adriana; Hoffman, Gabriel E; Roussos, Panos; Wisniewski, Thomas; Wegiel, Jerzy; Stutzmann, Grace E; Mufson, Elliott J; Ginsberg, Stephen D

Acta neuropathologica. 2024 Aug 06; 148:16

MethNet: a robust approach to identify regulatory hubs and their distal targets from cancer data

Sakellaropoulos, Theodore; Do, Catherine; Jiang, Guimei; Cova, Giulia; Meyn, Peter; Dimartino, Dacia; Ramaswami, Sitharam; Heguy, Adriana; Tsirigos, Aristotelis; Skok, Jane A

Nature communications. 2024 Jul 17; 15:6027

Integrative multi-omics profiling in human decedents receiving pig heart xenografts

Schmauch, Eloi; Piening, Brian; Mohebnasab, Maedeh; Xia, Bo; Zhu, Chenchen; Stern, Jeffrey; Zhang, Weimin; Dowdell, Alexa K; Kim, Jacqueline I; Andrijevic, David; Khalil, Karen; Jaffe, Ian S; Loza, Bao-Li; Gragert, Loren; Camellato, Brendan R; Oliveira, Michelli F; O'Brien, Darragh P; Chen, Han M; Weldon, Elaina; Gao, Hui; Gandla, Divya; Chang, Andrew; Bhatt, Riyana; Gao, Sarah; Lin, Xiangping; Reddy, Kriyana P; Kagermazova, Larisa; Habara, Alawi H; Widawsky, Sophie; Liang, Feng-Xia; Sall, Joseph; Loupy, Alexandre; Heguy, Adriana; Taylor, Sarah E B; Zhu, Yinan; Michael, Basil; Jiang, Lihua; Jian, Ruiqi; Chong, Anita S; Fairchild, Robert L; Linna-Kuosmanen, Suvi; Kaikkonen, Minna U; Tatapudi, Vasishta; Lorber, Marc; Ayares, David; Mangiola, Massimo; Narula, Navneet; Moazami, Nader; Pass, Harvey; Herati, Ramin S; Griesemer, Adam; Kellis, Manolis; Snyder, Michael P; Montgomery, Robert A; Boeke, Jef D; Keating, Brendan J

Nature medicine. 2024 May ; 30:1448-1460

Apolipoprotein E2 Expression Alters Endosomal Pathways in a Mouse Model With Increased Brain Exosome Levels During Aging

Peng, Katherine Y; Liemisa, Braison; Pasato, Jonathan; D'Acunzo, Pasquale; Pawlik, Monika; Heguy, Adriana; Penikalapati, Sai C; Labuza, Amanda; Pidikiti, Harshitha; Alldred, Melissa J; Ginsberg, Stephen D; Levy, Efrat; Mathews, Paul M

Traffic. 2024 May ; 25:e12937

Emergence and dissemination of SARS-CoV-2 XBB.1.5 in New York

GÃ¡mbaro, Fabiana; Duerr, Ralf; Dimartino, Dacia; Marier, Christian; Iturrate, Eduardo; Mulligan, Mark J; Heguy, Adriana; Dellicour, Simon

Virus evolution. 2024 May ; 10:veae035

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Genome Technology Center Featured Publications | NYU Langone Health