Genome Technology Center Featured Publications

Our staff members and collaborators frequently publish their research in leading peer-reviewed publications. Here is a selection of their recent accomplishments.

Selected Publications

Benefits of Maternal Choline Supplementation on Aged Basal Forebrain Cholinergic Neurons (BFCNs) in a Mouse Model of Down Syndrome and Alzheimer's Disease

Alldred, Melissa J; Pidikiti, Harshitha; Ibrahim, Kyrillos W; Lee, Sang Han; Heguy, Adriana; Chiosis, Gabriela; Mufson, Elliott J; Stutzmann, Grace E; Ginsberg, Stephen D

Biomolecules. 2025 Aug 05; 15:

Frontal cortex pyramidal neuron expression profiles differentiate the prodromal stage from progressive degeneration across the Alzheimer's disease spectrum

Labuza, Amanda; Alldred, Melissa J; Pidikiti, Harshitha; Malek-Ahmadi, Michael H; Lee, Sang Han; Heguy, Adriana; Coleman, Paul D; Chakrabarty, Souparna; Chiosis, Gabriela; Mufson, Elliott J; Ginsberg, Stephen D

Alzheimer's & dementia. 2025 Jul ; 21:e70395

Profiling lamina specific pyramidal neurons using postmortem human formalin fixed paraffin embedded frontal cortex tissue in combination with digital spatial profiling

Stanisavljevic, Aleksandra; Ibrahim, Kyrillos W; Stavrides, Philip H; Bare, Christopher; Alldred, Melissa J; Heguy, Adriana; Nixon, Ralph A; Ginsberg, Stephen D

Journal of neuroscience methods. 2025 Jun 03; 110512

Profiling hippocampal neuronal populations reveals unique gene expression mosaics reflective of connectivity-based degeneration in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease

Alldred, Melissa J; Ibrahim, Kyrillos W; Pidikiti, Harshitha; Lee, Sang Han; Heguy, Adriana; Chiosis, Gabriela; Mufson, Elliott J; Stutzmann, Grace E; Ginsberg, Stephen D

Frontiers in molecular neuroscience. 2025 Mar ; 18:1546375

Digital spatial profiling to predict recurrence in grade 3 stage I lung adenocarcinoma

Chang, Stephanie H; Mezzano-Robinson, Valeria; Zhou, Hua; Moreira, Andre; Pillai, Raymond; Ramaswami, Sitharam; Loomis, Cynthia; Heguy, Adriana; Tsirigos, Aristotelis; Pass, Harvey I

Journal of thoracic & cardiovascular surgery. 2024 Sep ; 168:648-657.e8

Cellular dynamics in pig-to-human kidney xenotransplantation

Pan, Wanqing; Zhang, Weimin; Zheng, Binghan; Camellato, Brendan R; Stern, Jeffrey; Lin, Ziyan; Khodadadi-Jamayran, Alireza; Kim, Jacqueline; Sommer, Philip; Khalil, Karen; Weldon, Elaina; Bai, Jiangshan; Zhu, Yinan; Meyn, Peter; Heguy, Adriana; Mangiola, Massimo; Griesemer, Adam; Keating, Brendan J; Montgomery, Robert A; Xia, Bo; Boeke, Jef D

Med (New York, N.Y.). 2024 Aug 09; 5:1016-1029.e4

Analysis of microisolated frontal cortex excitatory layer III and V pyramidal neurons reveals a neurodegenerative phenotype in individuals with Down syndrome

Alldred, Melissa J; Pidikiti, Harshitha; Ibrahim, Kyrillos W; Lee, Sang Han; Heguy, Adriana; Hoffman, Gabriel E; Roussos, Panos; Wisniewski, Thomas; Wegiel, Jerzy; Stutzmann, Grace E; Mufson, Elliott J; Ginsberg, Stephen D

Acta neuropathologica. 2024 Aug 06; 148:16

MethNet: a robust approach to identify regulatory hubs and their distal targets from cancer data

Sakellaropoulos, Theodore; Do, Catherine; Jiang, Guimei; Cova, Giulia; Meyn, Peter; Dimartino, Dacia; Ramaswami, Sitharam; Heguy, Adriana; Tsirigos, Aristotelis; Skok, Jane A

Nature communications. 2024 Jul 17; 15:6027

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Genome Technology Center Featured Publications | NYU Langone Health