Genome Technology Center Instruments | NYU Langone Health

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Genome Technology Center Genome Technology Center Instruments

Genome Technology Center Instruments

Experts at NYU Langone’s Genome Technology Center use the latest technologies in genome sequencing.

Illumina NovaSeq X-Plus

  • highest throughput of any production platform
  • lowest cost with more generated data
  • available 10B flow cells with 100, 200, 300 cycles
  • 8 lane flow cell
  • 25B 300 cycle flow cells coming in 4th quarter 2023

Illumina NovaSeq 6000

  • flagship sequencer for past several years
  • run variety of library prep samples

Single Cell library prep

  • 10x platform for single cell RNAseq
  • 10x multiome ATACseq & RNAseq from nuclei
  • 10x visium platform for FFPE material
  • 10x chromium connect for automated library prep
  • fluentbio Pipseq single cell RNAseq for cheaper alternative

PacBio Sequel IIe

  • long read sequencing with methylation data
  • de novo genome sequencing
  • amplicon sequencing
  • masseq for 10x single cell samples
  • isoseq for total RNA samples

Oxford Nanopore Promethion P24 and minion MK1c

  • long read sequencing with methylation data
  • de novo genome sequencing
  • amplicon sequencing
  • 10x cDNA sequencing for long reads
  • direct total RNA sequencing

Illumina NextSeq 2000

  • Sequence any library type on P1 & P2 flow cells
  • fast turnaround
  • custom primer sequencing

Illumina MiSeq

  • metagenomics
  • 16S ribosomal RNA (rRNA) sequencing
  • amplicon sequencing

Beckman Coulter Biomek SPRIworks HT

  • automated library prep
  • automated exome or targeted capture
  • automated quantitative polymerase chain reaction (qPCR) setup

Automated library prep

  • opentrons flex system
  • tecan fluent system

Nanostring nCounter

  • micro RNA (miRNA) and messenger RNA (mRNA) expression
  • copy-number variants
  • single-cell gene expression
  • geoMx preps

Bio-Rad QX200 Droplet Digital PCR

  • absolute quantification of RNA and DNA molecules
  • rare or low-frequency variants or mutation
  • pathogen detection

Covaris R230

  • DNA and chromatin shearing for next-generation sequencing (NGS) library preparation in 96 well plate format

Agilent 2100 Bioanalyzer

  • measures quantity and quality of RNA and DNA

Bio-Rad CFX384 Touch Real-Time PCR System

  • library prep quantification (please note: we do not offer qPCR as a service)

Agilent 2200 & 4200 TapeStation

  • automated benchtop system to measure the quality of biological samples from 2 to 96 samples at a time

Qubit 2.0 Fluorometer

  • quantification of double-stranded DNA (dsDNA)