The Preclinical Imaging Laboratory has three high-frequency ultrasound biomicroscopy scanners.

Fujifilm Vevo 3100 VisualSonics Ultrasound

A Fujifilm Vevo 3100 VisualSonics ultrasound system is in the Preclinical Imaging Laboratory, outside the specific-pathogen-free (SPF) barrier. The powerful scanner is equipped with linear-array technology with several high-frequency ultrasound transducers capable of real-time imaging, up to 300 frames per second. It can image various organs in living animals and can perform in utero imaging of the developing mouse embryo.

The system is equipped with complete animal setup and handling to achieve noninvasive in vivo imaging under accurate physiological conditions (temperature-controlled heated stage, gas anesthesia, and syringe injection system for simultaneous compound administration).

The system is bench mounted with an adjustable rail system custom designed for small-animal handling, positioning, and imaging. The transducer is fully adjustable using a Fujifilm Vevo MicroScan “stand and mount” platform, enabling fully adjustable X, Y, and Z positioning. It is augmented with a stepper motor for volumetric data set acquisition.

The system also has an injection setup composed of micromanipulation controls mounted on dedicated rail-system extensions to enable Y-axis stage adjustment. It can also assist image-guided injections. When used with targeted ultrasound contrast agent, the Fujifilm Vevo 3100 can be used for molecular imaging.

Fujifilm Vevo 770 VisualSonics Ultrasound

We offer a Fujifilm Vevo 770 VisualSonics ultrasound within the SPF barrier. The system can image the adult-mouse cardiovascular system as well as the major abdominal organs. It’s equipped with complete animal rail system and handling to achieve noninvasive in vivo imaging in real time at 100 frames per second under accurate physiological conditions (temperature-controlled heated stage, gas anesthesia, and syringe injection system for simultaneous compound administration).

Fujifilm Vevo 2100 VisualSonics Ultrasound

A Fujifilm Vevo 2100 VisualSonics ultrasound system is in the Joan and Joel Smilow Research Center, outside the SPF barrier. The powerful scanner is equipped with linear-array technology with several high-frequency ultrasound transducers capable of real-time imaging, up to 300 frames per second. It can image various organs in living animals and can perform in utero imaging of the developing mouse embryo.

The system is equipped with complete animal setup and handling to achieve noninvasive in vivo imaging under accurate physiological conditions (temperature-controlled heated stage, gas anesthesia, and syringe injection system for simultaneous compound administration).

The system is bench mounted with an adjustable rail system custom designed for small-animal handling, positioning, and imaging. The transducer is fully adjustable using a Fujifilm Vevo MicroScan “stand and mount” platform, enabling fully adjustable X, Y, and Z positioning. It is augmented with a stepper motor for volumetric data set acquisition.

The system also has an injection setup composed of micromanipulation controls mounted on dedicated rail-system extensions to enable Y-axis stage adjustment. It can also assist image-guided injections. When used with targeted ultrasound contrast agent, the Fujifilm Vevo 2100 can be used for molecular imaging.