Rapid Randomized Controlled Trial Lab | NYU Langone Health

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Healthcare Delivery System Redesign Rapid Randomized Controlled Trial Lab

Rapid Randomized Controlled Trial Lab

Led by Leora Horwitz, MD, MHS, the Rapid Randomized Controlled Trial (RCT) Lab, in the Center for Healthcare Innovation and Delivery Science, aims to transform NYU Langone into a learning healthcare system by using rapid-cycle randomized controlled trials to test simple, pragmatic ideas. Our goal is to identify strategies across our health system that can quickly change healthcare practice and be scaled nationally.

Our Approach

An RCT is a type of study in which participants are randomly assigned to the treatment or placebo group. The different groups allow researchers to determine the effects of the intervention while keeping other variables constant and reducing bias. The RCT is considered the gold standard of hypothesis testing. At our lab, we apply the RCT approach to test ideas in a cycle of rapidly iterated trials, which allows us to fine-tune each intervention based on data.

Our group has worked with 16 departments across NYU Langone and completed 15 trials, and we are currently involved in 4 ongoing trials, with 12 additional trials in the planning stage.

We work with your team to design and conduct a trial, guiding you on several key questions:

  • What options are being compared?
  • What is the target population? How will we identify them?
  • What is the outcome? How long will it take to determine?
  • What data collection measurements are needed?
  • What is the sample size?
  • Is the project meeting ethical and oversight requirements?

As part of our work with you, we assist with randomization methods and support your team in assessing results. We provide mentorship, design expertise, project management, IT support, data extraction, statistical analysis, regulatory reporting, and manuscript support.

Our Collaborators

Our collaborators work with us to develop and test randomized controlled trials of simple, pragmatic ideas.

Healthcare Innovation Bridging Research, Informatics, and Design Lab

The Healthcare Innovation Bridging Research, Informatics, and Design (HiBRID) Lab, based in the Division of Healthcare Delivery Science, works with peer researchers to design user-centered digital products for patients and the healthcare system, aimed at improving healthcare delivery and patient care.

Work with Us

Our lab is open to projects in any discipline within the NYU Langone system. Rapid RCT Lab projects must meet the following criteria:

  • involve a high volume of target patients or events
  • data are easily obtained and routinely collected
  • outcomes are short term—over a period of days or weeks
  • have a simple, pragmatic, trial design

If you have an idea for a project, please contact Ashley Bagheri, project manager, at ashley.bagheri@nyulangone.org or submit a proposal.