At NYU Langone Health, the VEXAS Syndrome Care Program provides comprehensive, personalized care for individuals diagnosed with VEXAS syndrome—a recently discovered condition that is caused by somatic mutations in the UBA1 gene and is characterized by progressive inflammatory and hematologic symptoms. A specialized team of geneticists, rheumatologists, and hematologists collaborates with researchers at the Center of Human Genetics and Genomics to integrate clinical expertise with advanced genomic, bioinformatic, and laboratory techniques. By bridging the clinic with scientific research, we aim to better understand the pathobiology of this complex disease and ultimately, develop targeted treatments and improve the quality of life for patients.