Endocrine Surgery Research | NYU Langone Health

Skip to Main Content
Division of Endocrine Surgery Endocrine Surgery Research

Endocrine Surgery Research

Faculty in NYU Langone’s Division of Endocrine Surgery conduct ongoing clinical and scientific research, in addition to treating patients who have endocrine conditions. Our goal is to learn more about the natural history of thyroid cancer and the molecular changes that may make some types of cancer more aggressive than others.

Through this type of research, we aim to individualize patient care by identifying those who need to be treated more aggressively, as well as those who may not need to be treated at all. We are continually evaluating new surgical techniques to further decrease the risk of thyroid and parathyroid surgery and minimize patient discomfort.

Our research, led by Kepal N. Patel, MD, seeks to understand the mechanisms controlling the mitogen-activated protein kinase (MAPK) pathway in order to provide valuable insight into thyroid progression. As the MAPK pathway has been implicated in other types of cancer, including pancreatic cancer, colon cancer, and melanoma, Dr. Patel’s research is applicable to multiple diseases.

The goal of our research program is to identify molecular factors that may serve as prognosticators and potential therapeutic targets for aggressive thyroid carcinoma. Dr. Patel was awarded a grant from the Thyroid, Head and Neck Cancer (THANC) Foundation in cooperation with the American Thyroid Association for his research in thyroid cancer.

Dr. Patel is also the lead author of the first set of evidence-based guidelines to surgically manage adult thyroid disease, including thyroid nodules and cancer. By describing and evaluating the evidence and risk–benefit ratio of clinical recommendations, the guidelines support clinical decision-making.

Endocrine Surgery Faculty Publications

Faculty in our division publish in the field’s most respected peer-reviewed publications.

A comprehensive review of interventional ablation techniques for the management of thyroid nodules and metastatic lymph nodes

Kuo, Jennifer H; Sinclair, Catherine F; Lang, Brian; Spiezia, Stefano; Yu, Mingan; Ha, Eun Ju; Na, Dong Gyu; Offi, Chiara; Patel, Kepal N; Baek, Jung Hwan

Surgery. 2021 Nov 11;

Predictive Value of a Genomic Classifier in Indeterminate Thyroid Nodules Based on Nodule Size

Dublin, Jared C; Papazian, Michael; Zan, Elcin; Oweity, Thaira; Sun, Wei; Jacobson, Adam; Patel, Kepal; Brandler, Tamar C; Givi, Babak

JAMA otolaryngology-- head & neck surgery. 2021 Nov 04;

Lymph node metastases in pediatric medullary thyroid carcinoma

Oliver, Jamie R; Patel, Kepal N; Chang, Clifford M; Baldwin, Chelsey K; Brar, Preneet C; Morris, Luc G T; Givi, Babak

Surgery. 2021 Sep ; 170:736-742

Stones left unturned: Missed opportunities to diagnose primary hyperparathyroidism in patients with nephrolithiasis

Lui, Michael S; Fisher, Jason C; Underwood, Hunter J; Patel, Kepal N; Ogilvie, Jennifer B

Surgery. 2021 Jul 27;

Nodal disease burden and outcome of medullary thyroid carcinoma

Moses, Lindsey E; Oliver, Jamie R; Rotsides, Janine M; Shao, Qianhui; Patel, Kepal N; Morris, Luc G T; Givi, Babak

Head & neck. 2021 Feb ; 43:577-584

The role of minimally invasive approaches to hepatic and splenic surgery

Pachter, H. Leon

Laparoscopic surgery. 2021 Jan 01; 5:?-?

Treatment of splenic cysts

Nowak, Brittany; Fielding, George Alexander; Leon Pachter, H.

Laparoscopic surgery. 2021 Jan 01; 5:?-?

Application and Utility of Radiofrequency Ablation in the Treatment of Benign Thyroid Nodules

Underwood, Hunter J.; Lui, Michael S.; Patel, Kepal N.

Current otorhinolaryngology reports. 2021 Jan 01; ?-?