Scientists using our mass spectrometry core lead a range of research projects that aim to characterize proteins responsible for key neuronal processes or disorders. Their ongoing projects include the following:

• Steven J. Burden, PhD: the role of signaling by MuSK in the neuromuscular synapse; protein clustering at the neuromuscular synapse
• Moses V. Chao, PhD: neurotrophin signaling
• Gabriela Chiosis, PhD (Memorial Sloan Kettering Cancer Center): composition of the epichaperome in health and disease
• David T. Chiu, MD: neuroregeneration
• Matthew Dalva, PhD (Thomas Jefferson University): ephrin phosphoproteomics
• Robert C. Froemke, PhD: role of oxytocin in maternal behavior
• Jorge A. Ghiso, PhD: characterization of beta amyloid peptides
• Barbara Hempstead, PhD (Weill Cornell Medicine): molecular mechanisms of neurotrophin signaling
• Bryen Jordan, PhD (Albert Einstein College of Medicine): activity-dependent changes in postsynaptic density composition
• Eric Klann, PhD (NYU’s Center for Neural Science): elF2-alpha phosphorylation in synaptic plasticity, memory, and brain disorders; translational control in synaptic plasticity and memory
• Cary Lai, PhD (Indiana University): neuregulin-ERBB signaling
• Efrat Levy, PhD (NYU Langone/Nathan Kline Institute for Psychiatric Research): characterization of exosomes in Alzheimer’s disease
• Charles R. Marmar, MD; Michael P. Bogenschutz, MD; and Esther Blessing, MD, PhD: use of cannabinoids to treat PTSD
• Paul M. Matthews, PhD (NYU Langone/Nathan Kline Institute for Psychiatric Research): role of apolipoprotein E (ApoE) alleles in Alzheimer’s disease susceptibility; mechanism of increased risk for Alzheimer’s disease in diabetes
• Ralph A. Nixon, MD, PhD (NYU Langone/Nathan Kline Institute for Psychiatric Research): neurofilament phosphorylation
• Dimitris G. Placantonakis, MD, PhD: metabolomics and proteomics of gliomagenesis
• Niels Ringstad, PhD: molecular mechanisms of functioning of sensory neurons in C. elegans
• Bernardo Rudy, MD, PhD: molecular components of A-type K+ channels; development and function of 5HT3aR-expressing cortical GABAergic interneurons
• Hyung Don Ryoo, PhD: retinal degeneration
• Martin Sadowski, MD, PhD: physical interaction between ApoE and amyloid-beta
• James L. Salzer, MD, PhD: phosphoproteomics of neuronal stimulation; mechanisms of node of Ranvier assembly
• Michael Schlame, MD: lipid analysis and metabolism, Barth syndrome, acrosomal biogenesis
• Einar M. Sigurdsson, PhD: epitope-specific targeting of tau aggregates
• Richard Tsien, DPhil: modulation of neurotransmission by Ca++ and activity