Archive of Select Faculty Publications

This page provides a selection of previous neuroscience faculty research publications. All of our faculty research is available through the Ehrman Medical Library search engines. In addition, please see a list highlighting Recent Faculty Publications

Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor.Cell  12/19/13
Christopher N. Parkhurst, Guang Yang, Ipe Ninan, Jeffrey N. Savas, John R. Yates III, Juan J. Lafaille, Barbara L. Hempstead, Dan R. Littman, Wen-Biao Gan

A modular gain-of-function approach to generate cortical interneuron subtypes from ES cells.Neuron  12/04/13
Edmund Au, Tanzeel Ahmed, Theofanis Karayannis, Shiona Biswas, Lin Gan, Gord Fishell

Inhibition-induced theta resonance in cortical circuits.Neuron  12/04/13
Eran Stark, Ronny Eichler, Lisa Roux, Shigeyoshi Fujisawa, Horacio G. Rotstein, and Gyorgy Buzsáki

Calcium-Permeable AMPA Receptors in the Nucleus Accumbens Regulate Depression-Like Behaviors in the Chronic Neuropathic Pain State Journal of Neuroscience  11/27/13
Yossef Goffer, Duo Xu, Sarah E. Eberle, James D'amour, Michelle Lee, David Tukey, Robert C. Froemke, Edward B. Ziff, and Jing Wang

Local Generation and Propagation of Ripples along the Septotemporal Axis of the HippocampusJournal of Neuroscience 10/23/13
Jagdish Patel, Erik W. Schomburg, Antal Berényi, Shigeyoshi Fujisawa, and György Buzsáki

A disinhibitory circuit mediates motor integration in the somatosensory cortex.Nature Neuroscience 10/06/13
Soohyun Lee, Illya Kruglikov, Z. Josh Huang, Gord Fishell, and Bernardo Rudy

Two novel tau antibodies targeting the 396/404 region are primarily taken up by neurons and reduce tau pathology. Journal of Biological Chemistry 10/02/13
Jiaping Gu, Erin Congdon, and Einar Sigurdsson

Lateral Entorhinal Modulation of Piriform Cortical Activity and Fine Odor Discrimination.Journal of Neuroscience 8/14/13
Julie Chapuis, Yaniv Cohen, Xiaobin He, Zhijan Zhang, Sen Jin, Fuqiang Xu, and Donald A. Wilson

De novo mutations in epileptic encephalopathies.Nature 8/11/13
Epi4K Consortium & Epilepsy Phenome/Genome Project (NYU Comprehensive Epilepsy Center)

Oxytocin enhances hippocampal spike transmission by modulating fast-spiking interneurons.Nature 8/04/13
Scott F. Owen, Sebnem N. Tuncdemir, Patrick L. Bader, Natasha N. Tirko, Gord Fishell, and Richard W. Tsien

Ionotropic Glutamate Receptors IR64a and IR8a Form a Functional Odorant Receptor Complex In Vivo in Drosophila.Journal of Neuroscience 6/26/13
Minrong Ai, Steven Blais, Jin-Yong Park, Soohong Min, Thomas A. Neubert, and Greg S. B. Suh

The autism brain imaging data exchange: towards a large-scale evaluation of the intrinsic brain architecture in autism. Molecular Psychiatry 6/18/13
A Di Martino, C-G Yan, Q Li, E Denio, F X Castellanos, K Alaerts, J S Anderson, M Assaf, S Y Bookheimer, M Dapretto, B Deen, S Delmonte, I Dinstein, B Ertl-Wagner, D A Fair, L Gallagher, D P Kennedy, C L Keown, C Keysers, J E Lainhart, C Lord, B Luna, V Menon, N J Minshew, C S Monk, S Mueller, R-A Müller, M B Nebel, J T Nigg, K O'Hearn, K A Pelphrey, S J Peltier, J D Rudie, S Sunaert, M Thioux, J M Tyszka, L Q Uddin, J S Verhoeven, N Wenderoth, J L Wiggins, S H Mostofsky and M P Milham

Peripheral elevation of TNF-α leads to early synaptic abnormalities in the mouse somatosensory cortex in experimental autoimmune encephalomyelitis. PNAS 6/18/13
Guang Yang, Christopher N. Parkhurst, Scott Hayes, and Wen-Biao Gan

Circadian glucocorticoid oscillations promote learning-dependent synapse formation and maintenance.Nature Neuroscience 4/28/13
Conor Liston, Joseph M Cichon, Freddy Jeanneteau, Zhengping Jia, Moses V Chao, and Wen-Biao Gan

Taste-independent nutrient selection is mediated by a brain-specific Na+/solute co-transporter in Drosophila.Nature Neuroscience 3/31/13
Monica Dus, Minrong Ai, and Greg S.B. Suh

Dedicated olfactory neurons mediating attraction behavior to ammonia and amines in Drosophila.PNAS 3/18/13
Soohong Min, Minrong Ai, Seul A Shin, and Greg S.B. Suh

Cortical response tracking the conscious experience of threshold duration visual stimuli indicates visual perception is all or none.PNAS 3/18/13
Krithiga Sekar, William M. Findley, David Poeppel, and Rodolfo R. Llinás

Dipeptidyl-peptidase-like-proteins confer to Kv4-mediated A-type K+ channels high sensitivity to the scorpion toxin AmmTX3.Journal of Physiology 2/25/13
Jon K. Maffie, Elena Dvoretskova, Pierre Edouard Bougis, Marie-France Martin-Eauclaire and Bernardo Rudy

Testosterone Depletion in Adult Male Rats Increases Mossy Fiber Transmission, LTP, and Sprouting in Area CA3 of Hippocampus The Journal of Neuroscience 2/6/13
Vanessa A. Skucas, Aine M. Duffy, Lauren C. Harte-Hargrove, Alejandra Magagna-Poveda, Thomas Radman, Goutam Chakraborty, Charles E. Schroeder, Neil J. MacLusky, and Helen E. Scharfman

TRPM2 Channels Are Required for NMDA-Induced Burst Firing and Contribute to H2O2-Dependent Modulation in Substantia Nigra Pars Reticulata GABAergic Neurons The Journal of Neuroscience 1/16/13
Christian R. Lee, Robert P. Machold, Paul Witkovsky, and Margaret E. Rice

Genetic and functional modularity of hox activities in the specification of limb-innervating motor neurons PLOS Genetics 1/9/13
Julie Lacombe, Olivia Hanley, Heekyung Jung, Polyxeni Philippioud, Gulsen Surmeli, Jonathan Grinstein, and Jeremy S. Dasen

Neocortical Somatostatin-Expressing GABAergic Interneurons Disinhibit the Thalamorecipient Layer Neuron 1/9/13
Han Xu, Hyo-Young Jeong, Robin Tremblay, and Bernardo Rudy

Septal nuclei enlargement in human temporal lobe epilepsy without mesial temporal sclerosis.Neurology 1/9/13
Tracy Butler, Laszlo Zaborszky, Xiuyuan Wang, Carrie R. McDonald, Karen Blackmon, Brian T. Quinn, Jonathan DuBois, Chad Carlson, William B. Barr, Jacqueline French, Ruben Kuzniecky, Eric Halgren, Orrin Devinsky, Thomas Thesen

Serial proton MR spectroscopy of gray and white matter in relapsing-remitting MS. Neurology 1/1/13
Ivan I. Kirov, Assaf Tal, James S. Babb, Joseph Herbert, and Oded Gonen

Sequential then interactive processing of letters and words in the left fusiform gyrus.Nature Communications 12/18/12
Thomas Thesen, Carrie R. McDonald, Chad Carlson, Werner Doyle, Syd Cash, Jason Sherfey, Olga Felsovalyi, Holly Girard, William Barr, Orrin Devinsky, Ruben Kuzniecky and Eric Halgren

Satb1 Is an Activity-Modulated Transcription Factor Required for the Terminal Differentiation and Connectivity of Medial Ganglionic Eminence-Derived Cortical InterneuronsJournal of Neuroscience 12/5/12
Jennie Close*, Han Xu*, Natalia De Marco García, Renata Batista-Brito, Elsa Rossignol, Bernardo Rudy, and Gord Fishell

The role of PR-Set7 in replication licensing depends on Suv4-20h Genes and Development 12/1/12
David B. Beck, Adam Burton, Hisanobu Oda, Celine Ziegler-Birling, Maria-Elena Torres-Padilla, and Danny Reinberg

Long-term Modification of Cortical Synapses Improves Sensory PerceptionNature Neuroscience 11/25/12
Robert C Froemke, Ioana Carcea, Alison J Barker, Kexin Yuan, Bryan A Seybold, Ana Raquel O Martins, Natalya Zaika, Hannah Bernstein, Megan Wachs, Philip A Levis, Daniel B Polley, Michael M Merzenich and Christoph E Schreiner

NMDA Receptor-Dependent Afterdepolarizations Are Curtailed by Carbonic Anhydrase 14: Regulation of a Short-Term Postsynaptic PotentiationJournal of Neuroscience 11/21/12
Sachin Makani, Huei-Ying Chen, Susana Esquenazi, Gul N. Shah, Abdul Waheed, William S. Sly, and Mitchell Chesler

IRK-1 Potassium Channels Mediate Peptidergic Inhibition of Caenorhabditis elegans Serotonin Neurons via a Go Signaling PathwayJournal of Neuroscience 11/14/12
Lesley Emtage, Sonya Aziz-Zaman, Olivia Padovan-Merhar, H. Robert Horvitz, Christopher Fang-Yen, and Niels Ringstad

Opposing regulation of dopaminergic activity and exploratory motor behavior by forebrain and brainstem cholinergic circuitsNature Communications 11/6/12
Jyoti C. Patel, Elsa Rossignol, Margaret E. Rice, and Robert P. Machold

Sustained Hox5 gene activity is required for respiratory motor neuron developmentNature Neuroscience 10/28/12 – Cover Image
Polyxeni Philippidou, Carolyn M. Walsh, Josée Aubin, Lucie Jeannotte, and Jeremy S. Dasen

The 4.1B cytoskeletal protein regulates the domain organization and sheath thickness of myelinated axonsGlia 10/26/12
Steven Einheber, Xiaosong Meng, Marina Rubin, Isabel Lam, Narla Mohandas, Xiuli An, Peter Shrager, Joseph Kissil, Patrice Maure, and James L. Salzer

REM Sleep Reorganizes Hippocampal ExcitabilityNeuron 9/20/12
Andres D. Grosmark, Kenji Mizuseki, Eva Pastalkova, Kamran Diba, and György Buzsáki

Obesity and Metabolic Syndrome and Functional and Structural Brain Impairments in AdolescencePediatrics 9/03/12
Po Lai Yau, Mary Grace Castro, BS, Adrian Tagani, Wai Hon Tsui, and Antonio Convit

Closed-Loop Control of Epilepsy by Transcranial Electrical StimulationScience 8/10/12
Antal Berényi, Mariano Belluscio, Dun Mao, and György Buzsáki

Traveling Theta Waves along the Entire Septotemporal Axis of the HippocampusNeuron 8/9/12
Jagdish Patel, Shigeyoshi Fujisawa, Antal Berényi, Sébastien Royer, and György Buzsáki

Lrp4 is a Retrograde Signal for Presynaptic Differentiation at Neuromuscular SynapsesNature 8/01/12
Norihiro Yumoto, Natalie Kim and Steven J. Burden

Dynamic FoxG1 Expression Coordinates the Integration of Multipolar Pyramidal Neuron Precursors into the Cortical PlateNeuron 6/21/12 – F1000 Evaluations
Goichi Miyoshi and Gord Fishell

Peripherin Is a Subunit of Peripheral Nerve Neurofilaments: Implications for Differential Vulnerability of CNS and Peripheral Nervous System AxonsJournal of Neuroscience 6/20/12
Aidong Yuan, Takahiro Sasaki, Asok Kumar, Corrinne M. Peterhoff, Mala V. Rao, Ronald K. Liem, Jean-Pierre Julien, and Ralph A. Nixon

Effects of Early-Life Abuse Differ across Development: Infant Social Behavior Deficits Are Followed by Adolescent Depressive-Like Behaviors Mediated by the AmygdalaJournal of Neuroscience 5/31/12
Charlis Raineki, Millie Rincón Cortés, Laure Belnoue, and Regina M. Sullivan

pHTomato, a red, genetically encoded indicator that enables multiplex interrogation of synaptic activityNature Neuroscience 5/27/12
Yulong Li and Richard W Tsien

CaV1 and CaV2 Channels Engage Distinct Modes of Ca2+ Signaling to Control CREB-Dependent Gene ExpressionCell 05/25/12 – F1000 Evaluations
Damian G. Wheeler, Rachel D. Groth, Huan Ma, Curtis F. Barrett, Scott F. Owen, Parsa Safa, and Richard W. Tsien

Dynamic changes in interneuron morphophysiological properties mark the maturation of hippocampal network activityJournal of Neuroscience 05/09/12
Camille Allene, Michel A. Picardo, Hélène Becq, Goichi Miyoshi, Gord Fishell, and Rosa Cossart

Control of timing, rate and bursts of hippocampal place cells by dendritic and somatic inhibitionNature Neuroscience 03/25/12
Sébastien Royer, Boris V Zemelman, Attila Losonczy, Jinhyun Kim, Frances Chance, Jeffrey C Magee, and György Buzsáki

ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse modelsScience 03/23/12 – F1000 Evaluations
Paige E. Cramer, John R. Cirrito, Daniel W. Wesson, C. Y. Daniel Lee, J. Colleen Karlo, Adriana E. Zinn, Brad T. Casali, Jessica L. Restivo, Whitney D. Goebel, Michael J. James, Kurt R. Brunden, Donald A. Wilson, Gary E. Landreth

Influence of Synaptic Vesicle Position on Release Probability and Exocytotic Fusion ModeScience 03/16/12 – F1000 Evaluations
Hyokeun Park, Yulong Li, and Richard W. Tsien

Opposite effects of fear conditioning and extinction on dendritic spine remodellingNature 02/19/12 – F1000 Evaluation
Cora Sau Wan Lai, Thomas F. Franke, and Wen-Biao Gan

The BDNF Val66Met Polymorphism Impairs Synaptic Transmission and Plasticity in the Infralimbic Medial Prefrontal CortexJournal of Neuroscience 02/15/12
Siobhan S. Pattwell, Kevin G. Bath, Rosalia Perez-Castro, Francis S. Lee, Moses V. Chao, and Ipe Ninan

Assembly and Maintenance of Nodes of Ranvier Rely on Distinct Sources of Proteins and Targeting MechanismsNeuron 01/12/12 – Cover Image, Video Abstract, F1000 evaluations
Yanqing Zhang, Yoko Bekku, Yulia Dzhashiashvili, Stephen Armenti, Xiaosong Meng, Yo Sasaki, Jeffrey Milbrandt, and James L. Salzer

Cross-Frequency Phase-Phase Coupling between Theta and Gamma Oscillations in the HippocampusJournal of Neuroscience 01/11/12
Mariano A. Belluscio, Kenji Mizuseki, Robert Schmidt, Richard Kempter, and György Buzsáki

BDNF and glucocorticoids regulate corticotrophin-releasing hormone (CRH) homeostasis in the hypothalamus PNAS – 01/09/12 – F1000 Evaluation
Freddy D. Jeanneteau, W. Marcus Lambert, Naima Ismaili, Kevin G. Bath, Francis S. Lee, Michael J. Garabedian, and Moses V. Chao

Heterogeneous reallocation of presynaptic efficacy in recurrent excitatory circuits adapting to inactivityNature Neuroscience 12/18/11
Ananya Mitra, Siddhartha S Mitra, and Richard W Tsien

Bidirectional plasticity of cortical pattern recognition and behavioral sensory acuityNature Neuroscience 11/20/11
Julie Chapuis and Donald A Wilson

Sensory network dysfunction, behavioral impairments, and their reversibility in an Alzheimer's β-amyloidosis mouse modeJournal of Neuroscience 11/02/11
Daniel W. Wesson, Anne H. Borkowski, Gary E. Landreth, Ralph A. Nixon, Efrat Levy, and Donald A. Wilson

Synaptic action of the olivocerebellar system on cerebellar nuclear spike activityJournal of Neuroscience 10/12/11
Timothy A. Blenkinsop and Eric J. Lang

A 4 Hz Oscillation Adaptively Synchronizes Prefrontal, VTA, and Hippocampal ActivitiesNeuron 10/06/11
Shigeyoshi Fujisawa and György Buzsáki

Glucocorticoids are critical regulators of dendritic spine development and plasticity in vivoPNAS 09/20/11
Conor Liston and Wen-Biao Gan

Masked excitatory crosstalk between the ON and OFF visual pathways in the mammalian retinaJournal of Physiology 09/15/11
Reza Farajian, Feng Pan, Abram Akopian, Béla Völgyi, and Stewart A. Bloomfield

Synaptic autoregulation by metalloproteases and γ-secretaseJournal of Neuroscience 08/24/11
Sophie Restituito, Latika Khatri, Ipe Ninan, Paul M. Mathews, Xin Liu, Richard J. Weinberg, and Edward B. Ziff

Hippocampal CA1 pyramidal cells form functionally distinct sublayersNature Neuroscience 08/07/11 – F1000 Evaluation
Kenji Mizuseki, Kamran Diba, Eva Pastalkova, and György Buzsáki

Taste-independent detection of the caloric content of sugar in DrosophilaPNAS 07/12/11
Monica Dus, SooHong Min, Alex C. Keene, Ga Young Lee, and Greg S. B. Suh

Semaphorin 3A induces CaV2.3 channel-dependent conversion of axons to dendritesNature Cell Biology 06/13/11
Makoto Nishiyama, Kazunobu Togashi, Melanie J. von Schimmelmann, Chae-Seok Lim, Shin-ichi Maeda, Naoya Yamashita, Yoshio Goshima, Shin Ishii, and Kyonsoo Hong

Mouse model of Timothy syndrome recapitulates triad of autistic traitsPNAS 06/10/11
Patrick L. Bader, Mehrdad Faizi, Leo H. Kim, Scott F. Owen, Michael R. Tadross, Ronald W. Alfa, Glenna C. L. Bett, Richard W. Tsien, Randall L. Rasmusson, and Mehrdad Shamloo

Relationships between Hippocampal Sharp Waves, Ripples, and Fast Gamma Oscillation: Influence of Dentate and Entorhinal Cortical ActivityJournal of Neuroscience 06/8/2011
Sullivan D, Csicsvari J, Mizuseki K, Montgomery S, Diba K, Buzsáki G.

Neuronal activity is required for the development of specific cortical interneuron subtypesNature 04/21/2011
Natalia V. De Marco García, Theofanis Karayannis, and Gord Fishell

Impairment of select forms of spatial memory and neurotrophin-dependent synaptic plasticity by deletion of glial aquaporin-4Journal of Neuroscience 04/27/2011
Skucas VA, Mathews IB, Yang J, Cheng Q, Treister A, Duffy AM, Verkman AS, Hempstead BL, Wood MA, Binder DK, Scharfman HE

Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidationPNAS 02/22/2011
Hoeffer CA, Cowansage KK, Arnold EC, Banko JL, Moerke NJ, Rodriguez R, Schmidt EK, Klosi E, Chorev M, Lloyd RE, Pierre P, Wagner G, LeDoux JE, Klann E.

Functional identification of an aggression locus in the mouse hypothalamusNature 02/10/2011
Lin D, Boyle MP, Dollar P, Lee H, Lein ES, Perona P, Anderson DJ.

Spontaneous activity signatures of morphologically identified interneurons in the vestibulocerebellumJournal of Neuroscience 01/12/2011
Ruigrok TJ, Hensbroek RA, Simpson JI.

Beta Ca2+/CaM-dependent kinase type II triggers upregulation of GluA1 to coordinate adaptation to synaptic inactivity in hippocampal neuronsPNAS 01/11/2011
Groth RD, Lindskog M, Thiagarajan TC, Li L, Tsien RW

Receptor-type guanylate cyclase is required for carbon dioxide sensation by Caenorhabditis elegansPNAS 01/04/2011
Hallem EA, Spencer WC, McWhirter RD, Zeller G, Henz SR, Rätsch G, Miller DM 3rd, Horvitz HR, Sternberg PW, Ringstad N

The largest group of superficial neocortical GABAergic interneurons expresses ionotropic serotonin receptorsJournal of Neuroscience 12/15/2010
Lee S, Hjerling-Leffler J, Zagha E, Fishell G, Rudy B

Acid Sensing by the Drosophila Olfactory systemNature 12/02/2010
Minrong Ai, Soohong Min, Yael Grosjean, Charlotte Leblanc, Rati Bell, Richard Benton, and Greg S. B. Suh

Support for a synaptic chain model of neuronal sequence generationNature 11/18/2010
Long MA, Jin DZ, Fee MS.

The MAP kinase phosphatase MKP-1 regulates BDNF-induced axon branchingNature Neuroscience 11/13/2010
Jeanneteau F, Deinhardt K, Miyoshi G, Bennett AM, Chao MV.

Exon junction complex subunits are required to splice Drosophila MAP kinase, a large heterochromatic geneCell 10/15/2010
Roignant JY, Treisman JE

Global control of motor neuron topography mediated by the repressive actions of a single hox geneNeuron 09/09/2010
Jung H, Lacombe J, Mazzoni EO, Liem KF Jr, Grinstein J, Mahony S, Mukhopadhyay D, Gifford DK, Young RA, Anderson KV, Wichterle H, Dasen JS.

Subthreshold membrane potential oscillations in inferior olive neurons are dynamically regulated by P/Q- and T-type calcium channels: a study in mutant miceJournal of Physiology 08/10/2010
Choi S, Yu E, Kim D, Urbano FJ, Makarenko V, Shin HS, Llinás RR.

Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutationsCell 06/25/2010
Lee JH, Yu WH, Kumar A, Lee S, Mohan PS, Peterhoff CM, Wolfe DM, Martinez-Vicente M, Massey AC, Sovak G, Uchiyama Y, Westaway D, Cuervo AM, Nixon RA

Developmental sensory experience balances cortical excitation and inhibitionNature 06/17/2010
Dorrn AL, Yuan K, Barker AJ, Schreiner CE, Froemke RC

Stably maintained dendritic spines are associated with lifelong memoriesNature 12/17/2009
Yang G, Pan F, Gan WB

Local changes in the excitability of the cerebellar cortex produce spatially restricted changes in complex spike synchronyJournal of Neuroscience 11/11/2009
Marshall SP, Lang EJ

Transitions in infant learning are modulated by dopamine in the amygdalaNature Neuroscience 11/2009
Barr GA, Moriceau S, Shionoya K, Muzny K, Gao P, Wang S, Sullivan RM.

Mitochondria are the source of hydrogen peroxide for dynamic brain-cell signalingJournal of Neuroscience 07/15/2009
Bao L, Avshalumov MV, Patel JC, Lee CR, Miller EW, Chang CJ, Rice ME

Lrp4 is a receptor for Agrin and forms a complex with MuSKCell 10/18/2008
Kim N, Stiegler AL, Cameron TO, Hallock PT, Gomez AM, Huang JH, Hubbard SR, Dustin ML, Burden SJ