New York City, with a population of more than eight million people, is the largest city in the United States and one of the largest cities in the world. As a global hub for business and commerce, it is at the center of major financial, cultural, political, and commercial operations, along with its world-renowned research, technology, and scientific facilities, and major academic institutions.

The city has long been famous for its artistic and creative force, as well as its cultural and architectural landmarks, and New York continues to welcome a dynamic and cutting-edge number of individuals from around the world who provide the foundation for the city’s unparalleled strength and diversity. New York embraces a vibrant, cosmopolitan spirit and it is comprised of a varied and multi-ethnic international community, whose members live in the five boroughs that make up the city, The Bronx, Brooklyn, Manhattan, Queens, and Staten Island, as well as in the metropolitan area beyond the city limits.

A wide selection of highly educated people with post-secondary degrees live in New York and the city has attracted at least 127 Nobel Prize winners who have either taught or studied here. In fact, New York has the highest concentration of science students and postdocs in the USA, while the city alone grants more PhDs in life sciences than 48 other US states, a number in degrees that is exceeded only by California and New York State itself. Along with the Boston area, New York leads all other areas as a recipient in NIH grant dollars and funding. Scientific institutions in the New York metropolitan area have generated the largest number of biotechnology-related patents in the country. Its unmatched cross-disciplinary strengths as a nexus for humanities, arts, and sciences have made the city a magnet for scientists and scholars of the highest calibers in all aspects of research. Within this remarkable community, New York University, founded in 1831, has achieved a distinction as a center for excellence among the leading institutions of learning.

NYU has been the academic home to an extraordinary range of scientists. Among the university’s faculty are MacArthur Fellows, Guggenheim Fellows, Howard Hughes Medical Institute Investigators, Lasker Award recipients, Nobel Prize winners, members of the Institute of Medicine, and other members of the National Academy of Sciences and the American Academy of Arts and Sciences.

Some of the most notable students and researchers at NYU include Eric Kandel, 2000 Nobel Laureate in Physiology or Medicine; Arthur Kornberg, 1959 Nobel Laureate in Physiology or Medicine; Saul Krugman, inventor of a hepatitis B vaccine; Matthew Scharff, B cell biology researcher; Clifford Shull, 1994 Nobel Laureate in Physics; George Todaro, graduate of the Department of Pathology and inventor of the 3T3 cell line; and Rosalyn Yalow, 1977 Nobel Laureate in Physiology or Medicine.

Famous faculty members at NYU include longtime Department of Pathology member Baruj Benacerraf, 1980 Nobel Laureate in Physiology or Medicine; Robert Engle, 2003 Nobel Laureate in Economics; Severo Ochoa, 1959 Nobel Laureate in Physiology or Medicine; Lewis Thomas, author of The Lives of a Cell and former Chair of the Department of Pathology; and Avram Hershko, 2004 Nobel Laureate in Chemistry for his work on ubiquitin-mediated protein degradation, who is an Adjunct Professor of Pathology at the NYU School of Medicine.

As the largest basic science department in the NYU School of Medicine, the Department of Pathology headquarters are on the fifth floor of the Medical Science Building, along First Avenue on the East Side of Manhattan, where the Chair and the administrative staff are situated and where many of the basic science faculty maintain research laboratories and offices. The faculty of the Department of Pathology, comprised of basic research scientists and practicing clinical pathologists, can be found at numerous locations—in the School of Medicine, Tisch Hospital, Bellevue Hospital Center, the VA Medical Center, the NYU Hospital for Joint Diseases, the Smilow Research Building, the NYU Clinical Cancer Center, and the Skirball Institute of Biomolecular Medicine.

These faculty members are at the heart of the sterling qualities that characterize the Department of Pathology—qualities that are manifested in its scholarship, its environment, and its spirit of community. We have a core of excellent scientists and clinicians in the Department who are renowned for their scientific rigor and creativity and who have made key contributions to our understanding of disease. Moreover, we are witnessing a renaissance in science here in Manhattan that is unlike anything we have seen for decades. The Department’s location contributes to this development. Given that both clinical and translational research require a large and diverse patient population, there are few cities in the world that can match the patient resources of New York.

Finally, a number of our best scientists and clinicians are naturally collegial people who are in academics or in medicine because they are stimulated by intellectual inquiry and want to contribute both to the creation and dissemination of knowledge and to patient care. They are loyal to the School and Hospital but not complacent, and they share an aspiration and commitment to make the Department of Pathology home to the next generation of clinical and intellectual leaders.

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