Available Positions for Postdoctoral Fellows
At NYU Grossman School of Medicine, we frequently post new opportunities for postdoctoral fellows to join our team of world-class biomedical investigators.
If you are interested in applying for an available position, please contact the principal investigator directly using the contact information included with the position listing. You might find additional postdoc and research opportunities by searching the NYU Grossman School of Medicine website for a researcher or department that interests you.
NYU Grossman School of Medicine researchers who have an available postdoctoral position they would like to add to this list can submit the new postdoctoral position submission form.
Current postdocs nearing the end of their appointment can log into the postdoc community using their Kerberos ID to browse a list of job openings. Faculty and administrators from outside institutions who wish to add a job opening to this list can do so by submitting a career opportunity form.
NYU Grossman School of Medicine is an equal opportunity employer committed to fostering diversity for postdoctoral fellows in the workplace. The following positions offer competitive salaries, excellent benefits, and eligibility for student housing.
Tissue Regeneration and Translational Medicine—June 22, 2021
An immediate postdoctoral position with a focus on tissue regeneration and translational medicine is available in the laboratory of Leslie I. Gold, PhD. The candidate will conduct basic science research in NYU Langone’s Department of Medicine (Division of Translational Medicine) and Department of Pathology and have an opportunity to work with Tissue Regeneration Sciences, a biotech startup. This position is an excellent and exciting opportunity to gain exposure to all aspects of translational medicine (patent law, formulation, pharmacodynamics and toxicology, clinical trials, and FDA regulations), while continuing to explore the basic science mechanisms related to the novel functions of calreticulin for a variety of clinical applications.
Our laboratory discovered that the calcium-binding endoplasmic reticulum chaperone protein, calreticulin (CRT), has profound positive biological effects on tissue regeneration, creating an exciting new research field that extends into skin/wound and ophthalmic regeneration, and epidermal (hair follicle neogenesis). Ongoing studies are focused on understanding the mechanisms and pathways involved in these novel extracellular functions of CRT as well as structure and function relationships of the molecule.
We prefer candidates who demonstrate the ability to be creative and highly motivated, can work independently, and have a strong background in tissue culture, cell biology, and general molecular biology and biochemical techniques, including migration assays. NYU Langone provides a highly enriched and interactive basic science environment and well-renowned young scientist programs for independent growth. This position is limited to U.S. citizens or candidates with a green card, current J-1 visa, or other visa. Please send your CV and at least three references to Dr. Gold at firstname.lastname@example.org.
Neural Circuits in Alzheimer’s Disease—June 11, 2021
A National Institutes of Health-funded postdoctoral position is available immediately in the laboratory of Arjun V. Masurkar, MD, PhD, part of the Center for Cognitive Neurology in NYU Grossman School of Medicine’s Department of Neurology. The postdoctoral fellow will study the pathophysiology of memory deficits in Alzheimer’s disease as part of a multidisciplinary team. The position is funded by an RF1 grant from the National Institute on Aging.
The postdoc will learn to combine cutting-edge techniques (in vitro electrophysiology, in vivo microendoscopic calcium imaging, optogenetics, and behavior) to study memory circuit dysfunction in animal models of Alzheimer’s disease. This is part of a larger research project that aims to understand the differential vulnerability of hippocampal subcircuits to amyloid and tau pathology, from molecular to behavioral levels.
The overarching goal of Dr. Masurkar’s research is to improve the detection, tracking, and treatment of early Alzheimer’s disease by studying the mechanisms of early symptoms via a “bench-to-bedside” approach. This is an outstanding opportunity to work independently on a high impact, state-of-the-art project in a stimulating, translational research environment.
Candidates must possess the following qualifications:
- PhD or equivalent in neuroscience or a related field
- experience with in vitro electrophysiology, in vivo imaging/electrophysiology, and/or behavior is desired but there are opportunities for training for otherwise exceptional candidates
- independent conduct and development of research projects
- excellent scientific productivity evidenced by publication record
- excellent communication and interpersonal skills
Applicants should send a CV, a cover letter with a statement that includes research goals and the candidate’s date of availability, and contact information for three references to Dr. Masurkar at email@example.com.
Protein Folding Disorders—June 3, 2021
Several full-time postdoctoral research positions are currently available in the laboratory of Jorge A. Ghiso, PhD, part of NYU Langone’s Department of Pathology. The team has a long-standing interest and research experience in the molecular basis of disorders of protein folding, with particular emphasis in cerebral amyloidosis, Alzheimer’s disease, and related neurodegenerative disorders.
The postdoctoral fellow will be involved in one of the following National Institutes of Health (NIH)-sponsored translational projects:
- assessment and pharmacologic in vitro and in vivo modulation of the molecular mechanisms by which abnormal protein conformations affect the cellular pathways regulating the homeostatic and metabolic integrity of brain cells
- translation approaches for the modulation of brain clearance mechanisms of the heterogeneous amyloid species that populate human interstitial and cerebrospinal fluids as well as parenchymal and cerebrovascular deposits in Alzheimer’s disease, utilizing transgenic mouse models to understand their pathophysiological impact in disease progression
Highly motivated, organized, and creative individuals with good communication skills and the ability to work independently are encouraged to apply. Preference will be given to candidates with a PhD in life sciences or related fields with strong background in proteomics/genomics and experience in cell culture and animal handling.
Interested applicants should send their CV, a letter of intent describing their motivations to apply, and contact information for professional references to Dr. Ghiso at firstname.lastname@example.org.
Molecular Epidemiology of Cancer Health Disparities—May 25, 2021
The Department of Population Health and Perlmutter Cancer Center at NYU Langone Health are seeking applications from strong candidates for a postdoctoral fellowship position in cancer epidemiology. The postdoctoral fellow will work with faculty on multiple National Institutes of Health (NIH) funded, large-scale, molecular epidemiological studies. These projects involve examining racial disparities in cancer, with a focus on the discovery of novel human microbiota and microbiota–tumor immune interactions in cancer development and therapy response. Our research resources involve molecular and genetic consortia in large-scale cohorts and clinical trials, including harmonized detailed epidemiological, lifestyle, and clinical data.
The postdoc works with a highly collaborative multidisciplinary research team to perform cutting edge analyses, implement novel statistical methodology, incorporate functional microbiome information, and publish research findings. Opportunities also exist for experience in grant writing and study management, as well as contributing to other manuscripts as a co-author. Our institution provides a strongly supportive academic and multidisciplinary research environment, and the fellow will be able to take full advantage of training, education, and mentorship opportunities offered.
A PhD or equivalent degree in epidemiology or related areas is required. We are seeking a highly motivated individual with excellent written and verbal communication skills, who is able to work in a highly collaborative, fast-paced environment. Expertise in the analysis of molecular and genetic data and in computational methods for complex, high-dimensional genotype data is desirable.
If you are interested in applying, please attach a cover letter, resume/CV, and contact information for three professional references. Please address inquiries to principal investigators Jiyoung Ahn, PhD, at email@example.com, or Richard B. Hayes, DDS, MPH, PhD, at firstname.lastname@example.org.
Vascular Biology, Immunology, and Inflammation in Relation to Atherosclerosis—May 24, 2021
The laboratory of Chiara Giannarelli, MD, PhD, associate professor of cardiology and pathology, at NYU Langone’s Department of Medicine, has openings for talented recent graduates of PhD programs in areas related to atherosclerosis, including vascular biology, immunology, and inflammation.
Atherosclerosis is the underlying cause of heart disease. Our lab has pioneered single-cell studies on the immune landscape in atherosclerotic lesions in the arteries of patients. This work has led to the discovery of immune alterations of T cells associated with stroke and has resulted in publications that rank in the top 1% of citations in the field.
The Giannarelli Lab is part of the recently established Cardiovascular Research Center in the Leon H. Charney Division of Cardiology at NYU Langone, which is nationally recognized as one of the finest medical research institutions in the United States. Collaborations with other outstanding investigators at NYU Langone are an integral part of our research projects and expand the training depth that the successful applicant experiences.
Our postdocs work with mouse and cell culture models and CRISPR screens. The work includes single-cell RNA sequencing, CyTOF, and in situ single-cell analyses, and involves collaborating with other lab members and outside laboratories. Independence will be encouraged as the postdoc gains experience. In consultation with Dr. Giannarelli, fellows design experiments, carry them out, interpret the results, present findings at lab meetings, and prepare written summaries of the research for presentations and publication.
To apply, please send your CV, research experience, and contact information for professional references to Dr. Giannarelli at email@example.com.
PrMEIR Postdoctoral Researcher—April 27, 2021
The Program for Medical Education Innovations and Research (PrMEIR) in the Division of General Internal Medicine and Clinical Innovation seeks a full-time post-doctoral researcher to be an essential member of its team. PrMEIR is dedicated to advancing medical education scholarship and instituting best practices for patient-centered, evidence-based medical education. Its mission is to support the development of research and practice that strengthen the links between a physician’s training and patient health and wellbeing. More specifically, PrMEIR aims to do the following:
- transform medical education by ensuring a steady pipeline of medical educators who are ready, willing, and committed to studying best practices in medical education
- educate future medical education researchers in effective educational strategies including performance-based assessments and simulation that links to patient outcomes
- provide a rich community of diverse stakeholders to ensure that medical education researchers that have a deep understanding of the medical education landscape
In order to do this, PrMEIR is offering a one-year postdoc position for a scholar who has obtained a doctoral degree in educational research, psychology, measurement, or a related field, and who is interested in additional research opportunities.
Areas of interest include the following:
- educational measurement and psychometrics
- natural language processing
- cognitive psychology
- learning theory
- large-scale assessments
Research expertise: In assessing research expertise, research scope, quality, depth, and breadth will be the prime consideration. Furthermore, we are also interested in someone with the capacity to interact and collaborate with other research faculty. Particular importance will be given to research within latent variable modeling, including structural equation modeling, item response theory, multilevel modeling, and mixed methods modeling.
Duties: The position includes research in psychometric modeling, data management and analysis, working as an integral member of a team of researchers, advising on measurement issues, and contributing to scholarly outputs.
Period of Employment: The position as a postdoctoral researcher is available initially for one academic year, 2021–2022. An extension for a second year is contingent on availability of funding.
Eligibility: To be eligible for appointment as a postdoctoral researcher, the applicant must hold a doctoral degree or possess the equivalent research expertise. Priority will be given to applicants who have obtained their doctoral degree or achieved equivalent competence. Strong organization, communication and writing skills are essential.
To apply, please send your resume and writing sample to Naya Jerome at firstname.lastname@example.org.
Optical Imaging Technologies for the Brain and Eye—April 27, 2021
Postdoctoral research positions are open for candidates interested in creating and developing the next generation of optical imaging technologies for the brain and eye. Applicants with a background, expertise, and interests in one or more of the following areas — biomedical optics and light-tissue interaction, medical signal and image processing, machine learning, fiber optics–photonics, diffuse optics, and microscopy — will be considered. Our group is NIH-funded and based in the Tech4Health Institute at NYU Grossman School of Medicine. View recent articles in Light: Science & Applications and Nature Communications about our work. See a full list of articles about our work.
Qualifications: The candidate must have a PhD in electrical engineering, biomedical engineering, physics, applied physics, or other relevant discipline. The candidate must also have demonstrated a strong background in one of the above areas as evidenced by publication of papers in peer-reviewed journals. Additionally, the candidate must be able to work both independently and as part of an interdisciplinary team. Candidates with broad expertise in programming–simulation, experimental optics, and biology–medicine are preferred. Interested applicants should submit the following materials in PDF format to email@example.com: updated curriculum vitae, contact information for three references, and copies of three publications from previous research on which the applicant has made a primary contribution.
Tumor Suppressive Organelles and Stem Cell Differentiation—April 21, 2021
The laboratory of Brian D. Dynlacht, PhD, at NYU Langone Health’s Department of Pathology, is continuing work on two exciting research projects and has immediate openings for postdoctoral fellows on both projects.
Primary Cilia as Tumor Suppressive Organelles
The Dynlacht Laboratory focuses on understanding the molecular controls that promote ciliogenesis, which plays a pivotal role in cell cycle progression and mitosis. The cilium is an important signaling organelle that plays a key role in regulating cell growth and differentiation, and the presence of primary cilium is associated with quiescence and differentiation. Defects in this structure are associated with many human developmental diseases and cancer. Yet the switching mechanisms that convert centrosomes to a primary cilium from which it is derived are not known.
We are interested in how primary cilia are normally assembled, what suppresses their formation in growing cells, and how these controls are subverted in pancreas and human breast cancers. We have performed genome-wide screens to uncover genes that, when over expressed, cause loss of cilia. Our team is now taking cell biological approaches toward uncovering the mechanisms that underly the function of these genes with the hope of developing novel therapeutic strategies to suppress aberrant proliferation in cancer cells. For this project, a strong interest and experience in cell biological methods and molecular biology is preferred.
Epigenetic Control of Stem Cell Differentiation
We use a combination of biochemical, genomic, and computational methods to dissect the epigenetic controls that govern cell cycle progression and mammalian differentiation. Using muscle differentiation as a model, we are attempting to unravel mechanisms that underlie the transition between growth and terminal differentiation. Using stem cells as muscle precursors, we are also attempting to reveal the epigenetic controls that determine whether a cell will adopt one mesodermal fate versus another. We are also exploring the topological changes in the three dimensional landscape of muscle stem cells by examining how interactions between genomic regions are rewired during differentiation into muscle cells.
The Dynlacht Lab has been committed to understanding the role of chromatin and gene expression in cell proliferation and differentiation using stem cell and breast cancer models for more than 20 years. Toward this effort, we are seeking candidates experienced in molecular biology to develop novel approaches and technologies for analyzing protein–chromatin interactions and epigenetic control of differentiation. Expertise with chromatin, gene expression, or transcription is preferred but not essential. The ideal candidate will help develop state-of-the-art and cutting-edge approaches toward understanding the role of protein interactions in assembly and activation of regulatory elements and gene activation and repression.
For an example of the research we perform in the lab, applicants are encouraged to read our latest paper on the topic, Zhang et al., 2020, Nat Commun. We are most interested in employing a combination of molecular biology, biochemistry, and computational methods to understand how chromatin topology is regulated in muscle stem cells.
For this project, candidates must have a PhD in molecular biology, biochemistry, or a related field and a strong interest in gene expression, chromatin, or both. Experience with computational methods, bioinformatics, and computer languages (e.g., Python, R) is a plus, as we seek to employ cutting-edge genomics and computational approaches. Highly interactive researchers are encouraged to apply.
If you are interested in either of these projects, please send a CV and a description of your interests to Dr. Dynlacht at firstname.lastname@example.org.
Humoral Responses in Immunology—April 15, 2021
Humoral responses are a core aspect of the immune response to infections and vaccines, yet we lack robust strategies to predict and precisely manipulate the antibody response. A postdoctoral fellowship is open in the laboratory of Ramin Herati, MD, part of NYU Langone Health’s Vaccine Center, to study human immune responses to immunological stimuli. Our work specifically focuses on the interactions of T follicular helper (Tfh) CD4 cells and B cells and the effects of these interactions on the antibody response.
Because we know that Tfh cells direct B cell responses in germinal centers, we hypothesize that a better understanding of the interaction between these cells may create opportunities to shape and manipulate humoral responses.
Our long-term goal is to understand humoral responses in different immunological contexts, including in the settings of infection, vaccines, cancer immunotherapy, and autoimmunity. The more that we understand about the interaction of Tfh and B cells, the better equipped we are to gain insight into these processes and identify opportunities to shape antibody responses. Researchers in our lab use a combination of approaches to study these interactions at the cellular and molecular levels. We hope to devise strategies that allow fine-grained control over antibody responses.
The postdoc will work on studies that are data-intensive and focused on human immune responses. Competitive candidates have a doctoral degree and a background in immunology, including substantial experience with flow cytometry, RNA sequencing, and data science. Passion, enthusiasm, and great communication skills are essential.
To apply, please send your CV, research experience, and contact information for professional references to Dr. Herati at email@example.com.
Immune Checkpoint Inhibition Therapies and Molecular Cancer Biology—April 14, 2021
A postdoctoral fellowship is available in the laboratory of Tomas Kirchhoff, PhD, at NYU Langone Health’s Perlmutter Cancer Center. We are a dynamic lab that studies host immunity in relation to the efficacy and toxicity of immune checkpoint inhibition (ICI) therapy. We use state-of-the art “-omics” approaches in large patient populations, in various immuno-oncology clinical trial settings and beyond.
Our work is positioned in a multidisciplinary environment that combines oncology, clinical trials, cancer genetics/immunology, and molecular cancer biology. The focus of this postdoc is the “multi-omics” investigation of large patient populations with the goal of discovering novel biomarkers of ICI outcomes that could potentially lead to actionable targets for improved ICI therapies for melanoma and other cancers. Successful candidates will be self-motivated and work well in a group environment.
Postdoc responsibilities include genomic data analysis from whole-genome sequencing, RNA-sequencing, epigenome-based next generation sequencing (ATAC-seq, CHIP-seq, Methylation-seq, etc.); high-throughput genotyping (SNP arrays, etc.); bioinformatics tool development; and manuscript and grant application preparation.
Candidates must have the following qualifications:
- a PhD in bioinformatics, computer science, biostatistics, genetics, or a related field
- extensive programming experience
- prior experience with large next generation sequencing (NGS) “omics” platforms
- knowledge of genomics and statistics
- good presentation skills
We prefer candidates who have experience in cancer genome analyses, data extraction from public databases, cancer biology, manuscript writing, and algorithm design. To apply, please send your CV to Dr. Kirchhoff at firstname.lastname@example.org.
Pancreatic Cancer Detection, Etiology, and Treatment—April 9, 2021
The laboratory of Diane M. Simeone, MD, at NYU Langone is looking to hire a postdoctoral fellow with a strong background in the fields of molecular biology, cell biology, cancer biology, or immunology. Dr. Simeone is an internationally renowned physician–scientist and the director of NYU Langone’s Pancreatic Cancer Center.
The Simeone Pancreatic Cancer Research Laboratory uses multiple, advanced genomic technologies to study the mechanisms of disease progression and to understand the biology that underlies this process to define new targets for therapy. We currently employ many in vitro and in vivo approaches, including patient derived organoids and tumor xenografts, as well as genetically engineered mouse models, to characterize and validate new targets and therapeutic strategies.
We seek a postdoc to work on projects that interrogate the role of microenvironment and the immune system in pancreatic cancer etiology and response to therapy. Our research program is expanding and focuses on different molecular subtypes of pancreatic cancer, including homologous recombinant-deficient pancreatic ductal adenocarcinoma. The successful candidate is a driven, creative, team-oriented individual, with a passion for translating fundamental biologic findings to the clinical setting.
Candidates should have broad experience in cell biology, biochemistry, and molecular biology. Experience with animal models (xenograft or genetically engineered mouse models) and multicolor flow cytometry analysis is valued positively.
A background in DNA damage signaling or immunology is desirable. Priority will be given to individuals with an outstanding publication record from prior graduate and/or postgraduate training and/or existing extramural funding. We welcome applications from both recent PhD recipients and individuals seeking additional postdoctoral training. Proficiency in English is required.
To apply, please submit a detailed CV, a brief statement of research interests that includes a description of previous research experience, and contact information for three references (email addresses and telephone numbers) to Jennifer Chun Kim at email@example.com. We will begin considering submitted applications immediately and continue until the position is filled.
About the Simeone Lab
Pancreatic ductal adenocarcinoma is a highly fatal malignancy that is projected to become the second leading cause of cancer-related deaths in the Unites States by 2030. The disease is characterized by delayed onset of symptoms, early metastasis, and frequent occurrence of resistance to clinically administered therapies.
The overarching goal of the Simeone Laboratory is to identify mechanisms and cellular pathways that regulate pancreatic cancer initiation and progression, as well as developing novel more effective therapeutics. We are focusing our efforts in several areas, including the role of ataxia telangiectasia group D complement (ATDC) in pancreatic cancer development, progression, and metastasis; introducing novel therapeutic approaches for DNA damage repair (DDR) gene–mutant pancreatic cancer; and the role of the pancreas immune microenvironment in disease progression.
Medical Ethics—April 1, 2021
Core qualifications include an excellent record of quality scholarship in research ethics and regulatory science, epidemiology, or clinical trial design, conduct, and analysis. Applicants must have a PhD, JD, or MD; a publication history; empirical research skills; and training in introductory-level data analysis methods. Familiarity with writing grant proposals is desirable, as is experience with institutional review board submissions. Candidates must be willing to work in a highly interdisciplinary environment.
This fellowship includes significant protected time to pursue research. Fellows are expected to engage in the following activities:
- mentor students on projects and research
- work on issues raised by the collection and use of real-world evidence from expanded access to unapproved drugs, vaccines, and other types of investigational agents
- work on issues related to the ethical and regulatory oversight of clinical trials,
- publish at least one scholarly article per year
- assist with the operations of the NYU Grossman School of Medicine Working Group on Compassionate Use and Preapproval Access (CUPA) and its Ethics of Real World Evidence project
- collaborate with other population health faculty
- participate in ethics teaching, as needed
The postdoctoral fellow reports directly to the director of the Division of Medical Ethics. The term of the fellowship is one year, but the position may be renewed for a second year. We offer a competitive stipend and benefits. We encourage candidates to apply who will contribute to the diversity of the NYU Langone Health community and who support our commitment to diversity and inclusion.
Applicants should email their cover letter, CV, and three letters of reference to Jessica Wico at firstname.lastname@example.org with “NYUSOM Search PostDoc” as the subject line. We are accepting applications until the position is filled.
Protein Engineering and Biologics Drug Discovery—March 29, 2021
The laboratory of Professor Shohei Koide, PhD, at NYU Grossman School of Medicine and NYU Langone’s Perlmutter Cancer Center is seeking dynamic and creative postdoctoral researchers to join the team. Postdocs in the Koide Lab participate in multi-disciplinary, collaborative projects that design and engineer novel binding proteins (e.g., synthetic antibodies and monobodies) for manipulating biological functions with high precision. Our ultimate goal is improving human health and elucidating fundamental cellular mechanisms. The cancer biologics platform of Perlmutter Cancer Center, which Professor Koide founded 5 years ago, is advancing several biologics therapeutics toward the clinic.
The available postdoc positions offer ample opportunities to gain expertise in diverse protein-engineering technologies including phage display, yeast surface display, and library design; in structurally and biophysically characterizing protein–protein interactions; and in controlling cellular functions. The postdocs will develop novel binding proteins against novel molecular targets and comprehensively characterize them in close collaboration with biology/disease experts. They also have opportunities to advance such molecules toward the clinic through industrial partnerships.
Candidates must have the following qualifications:
- a PhD in life sciences, chemistry, or bioengineering
- a strong publication record
- the ability to speak and write effectively in English
- strong communication, interpersonal, organizational and team skills
- be self-motivated, creative, and willing to take risks
Expertise in the following areas is advantageous: protein engineering, protein biochemistry, biophysics, structural biology, and/or cell signaling.
Apply by sending your current CV, a cover letter, and contact information for two or more references to Professor Koide at email@example.com.
Health x Housing Lab—March 29, 2021
The newly formed Health x Housing Lab in the Department of Population Health at NYU Grossman School of Medicine serves as a trusted broker of evidence-based information and guidance for initiatives, practice, and policy sitting at the intersection of health and housing. The lab’s work is guided by a commitment to improving health equity and is shaped by an advisory committee that includes people with lived experience of homelessness and/or housing instability.
We are seeking a fulltime postdoctoral fellow for a one-year position (a second year may be possible through mutual agreement) with an anticipated start date of July 1, 2021. The postdoc will lead Health x Housing Lab research projects, assist with other lab activities (e.g., participating in advisory committee meetings, contributing to seminars and policy-related activities), and learn and develop in their careers. The position is based in New York City, though work will temporarily be remote due to the COVID-19 pandemic.
The postdoc engages in all elements of research, from design through distribution. The fellow collaborates with community and academic partners on research; conducts statistical analyses independently; publishes first-authored manuscripts; and promotes research through conference presentations, policy reports, and other outlets. The exact research areas will be determined in consultation with the lab’s advisory committee but are expected to include projects with direct programmatic and/or policy relevance at the intersection of homelessness, housing, and health.
The goal of the postdoctoral fellow program is to help develop the next generation of faculty leaders in research that explores the intersection of health with homelessness and housing. The Department of Population Health hosts multiple seminars and professional development events weekly. All postdoctoral scholars have Individualized Development Plans made in conjunction with their mentors. Direct mentorship is provided by Health x Housing Lab leaders, including Kelly M. Doran, MD, and Amy Freeman, PhD.
Candidates must have the following qualifications:
- a doctoral degree (PhD, DrPh, or equivalent) in sociology, public health, population health, urban science/policy, public policy, health services research, epidemiology, biostatistics, or a related field
- dedication to research as a mechanism to improve health for marginalized populations
- proficiency with quantitative analysis—including with large datasets and using statistical software—and appropriate methodologic expertise
- the ability to perform methodologically sound cross-sectional and longitudinal analyses independently
- a track record of community-oriented, collaborative work and research, and ability to work effectively with diverse, interdisciplinary teams
- an understanding of and commitment to racial equity and housing justice
- evidence of strong writing and communication skills
- be a critical thinker and problem solver with the drive and demonstrated ability to translate ideas to action and complete projects effectively
Preference will be given to those with training and experience with qualitative methods, mixed methods, and/or community-based participatory research (CBPR) methods; experience with program and policy evaluation; relevant experience from outside academia; and strong foundational knowledge regarding housing and homelessness. Individuals from racial and/or ethnic groups that are underrepresented in medicine are encouraged to apply, as are individuals who have lived expertise with housing insecurity and/or homelessness.
Qualified candidates should send a CV, a cover letter describing your interest in the position, at least one academic writing example (an additional writing sample of an editorial, blog post, etc., may be provided), and information for three references. Please send application materials to Dr. Doran at firstname.lastname@example.org
Genetic and Tumor Immune Alterations Involved in Lung Cancer—March 19, 2021
The laboratory of Kwok-Kin Wong, MD, PhD at NYU Langone’s Laura and Isaac Perlmutter Cancer Center seeks a postdoc to participate in groundbreaking research to elucidate a fundamental understanding of the molecular underpinnings of lung cancer.
The postdoc works with leading academic clinicians and basic scientists and participates in pioneering work on the interplay of genetics, tumor immune infiltrate and therapeutics in preclinical lung cancer models, with the ultimate goal of developing rational treatment hypotheses to be tested in the clinic.
We aim to generate understanding of drug mechanism of actions and the development of novel treatments/combinations, as well as to identify novel biomarkers and new targets for novel therapeutics. The postdoc must effectively communicate their work by writing manuscripts and successfully publishing their results in premier journals.
To be considered, candidates must meet the following qualifications:
- be a recent PhD graduate in the cancer biology or immune oncology field
- have experience with molecular biology, genomic analysis, biochemistry and cell biology, in-vivo pharmacology, immunology, multi-flow cytometry, and cell culture
- have experience in the isolation and characterization of immune cells from primary human and mouse tissues
- demonstrate scientific rigor, scientific excellence, and technical excellence
- be independent, self-motivated, and innovative
- have a proven track record in the field of immunology/tumor immunology and/or oncology, including relevant publications
- have excellent written and oral communication skills
- be willing to seek out grant funding from external sources in support of their independent research (may participate in writing grant proposals)
- have outstanding interpersonal skills, strong work ethic, and organizational skills
- work productively and constructively in a team environment
- excel in a goal-oriented, multifaceted, and fast-moving team environment
Candidates who have experience with in vivo syngeneic mouse tumor models and 3D cell culture are preferred. Interested candidates should email Christina Almonte, project manager, at email@example.com.
About the Wong Lab
The Wong Laboratory is a translational oncology laboratory that seeks to improve outcomes for patients with lung cancer. The lab focuses on advancing the understanding of genetic and tumor immune alterations involved in lung tumorigenesis and pathogenesis. It has been an instrumental in evolving lung cancer into a genetically stratified disease and changing treatments for patients.
Our lab has pioneered generating and utilizing genetically engineered mouse lung cancer models to validate oncogenic drivers and test novel therapeutics against specific genetic oncogenic drivers. These preclinical models are now being used to lead the next revolution in lung cancer treatment through the combined assessment of genetics and tumor immunology. We are highly collaborative and work with numerous premier academic investigators and pharmaceutical companies to discovery and delineate the clinical path for novel therapeutic agents. The laboratory publishes in high impact journals, such as Nature, Nature Medicine, and Cancer Cell. Recent postdoctoral fellows who have trained in the Wong Laboratory are now investigators at numerous biotech and pharmaceutical companies.
Dr. Wong is an internationally renowned physician–scientist, NYU Grossman School of Medicine’s Anne Murnick Cogan and David H. Cogan Professor in Oncology, and chief of the Division of Hematology and Medical Oncology. He is also a member of the American Society of Clinical Investigation, the nation’s oldest honor society for physician–scientists.
In addition to world-class research facilities, NYU Langone’s Postdoctoral Training Program has a robust career development program. As one of only 17 schools to receive an NIH BEST (Broadening Experiences in Scientific Training) designation, we offer more than 30 courses and workshops on career planning, communication skills, negotiating, and conflict management, as well as career-specific training for careers in academia, pharma/biotech, science policy, medical communications, and many more. If you have questions about these programs, please email firstname.lastname@example.org.
Primary Cilia as Tumor Suppressive Organelles in Pancreatic Adenocarcinoma and Breast Cancer—March 4, 2021
A postdoctoral position is available in the Department of Pathology at NYU Langone for researchers who are interested in exploring the role of primary cilia as tumor suppressive organelles in pancreatic adenocarcinoma and breast cancer. The postdoc works in collaboration with the laboratories of Brian D. Dynlacht, PhD, and Diane M. Simeone, MD, a pancreatic cancer clinician–scientist and director of the Pancreatic Cancer Center.
The Dynlacht Lab is interested in understanding the molecular controls that promote ciliogenesis, which plays a pivotal role in cell cycle progression and mitosis. The cilium is a key signaling organelle that plays a key role in regulating cell growth and differentiation, and the presence of a primary cilium is associated with quiescence and differentiation. Defects in this structure are associated with many human developmental diseases and cancer. Yet the switching mechanisms that convert centrosomes to a primary cilium from which it is derived are not known. We are interested in how primary cilia are normally assembled and how these controls are subverted in human pancreatic adenocarcinoma and breast cancer.
We recently performed genome-wide screens to uncover genes, which when expressed cause the loss of cilia in a tissue culture model of triple negative breast cancer (Failler et al., 2021, Mol Biol Cell). In collaboration with the Simeone Pancreatic Cancer Research Lab, we have entered the second phase of this project and have begun to explore the role of ciliary suppression in the genesis of pancreatic adenocarcinoma.
This position leverages the combined expertise of the Dynlacht and Simeone research laboratories to investigate this important and understudied area of pancreatic cancer biology. Interested candidates should apply directly to Dr. Brian D. Dynlacht at email@example.com.
Systems Cancer Genetics—January 28, 2021
The Institute for Systems Genetics at NYU Langone and the laboratory of Teresa Davoli, PhD, seek highly motivated scientists who have great communication skills, a collaborative spirit, and a love for science to work on research projects that focus on cancer genetics and aneuploidy. Postdoctoral and staff scientist positions are available for wet lab, dry lab, or projects that involve a combination of both types of labs. Applicants with a background in genetics, molecular biology, and/or bioinformatics are encouraged to apply.
The maintenance of a normal complement of the genome is a requirement for the success of multicellular organisms. Aneuploidy refers to the presence of an abnormal (lower or higher than euploid) number of chromosomes or chromosome arms (segmental aneuploidy). Although detrimental at the organismal level, aneuploidy is extremely frequent (~90%) in human tumors (Beroukhim et al., 2010. Nature.). Despite the fact that aneuploidy is so frequent in cancer, little is known about whether and how aneuploidy contributes to tumorigenesis, and how aneuploidy could be targeted for cancer therapy.
The Davoli Lab recently conducted a combined analysis of point mutation and copy number data in primary human tumor samples and demonstrated that the distribution and potency of cancer driver genes on each chromosome or chromosome arm can predict the frequency of whole chromosome or chromosome arm aneuploidy across cancers (Davoli et al., 2013. Cell; Sack et al. 2018. Cell). This suggests that the recurrent patterns of aneuploidy in cancer act as driver events during tumorigenesis.
More recently, we expanded analysis to datasets from primary human tumors and have identified an interesting relationship between the level of cancer aneuploidy and the extent of tumor immune infiltrate (Davoli et al., 2017. Science).Our ongoing research interest is to determine whether and how cancer aneuploidy regulates different aspects of cancer development using a combination of experimental and computational approaches.
In this position, the postdoctoral researcher or staff scientist receives training on the use of state-of-the-art cancer genetics approaches and genomics analyses of patient datasets. Our research may require working with mice, including mouse models of human tumors, to test hypotheses from in vitro experiments.
Candidates must have the following qualifications:
- a PhD in biology or bioinformatics or an MD
- a strong research background in cell biology, cancer biology, or genome instability
- a robust publication record
- a great interest and excitement for systems genetics and cancer
The Institute for Systems Genetics was established in January 2014 by Jef D. Boeke, PhD, with the mission of performing innovative science in the fields of systems biology and genetics and genomics. We work with a diverse group of human- and model-organism geneticists, technology developers in “omics,” computational biologists, and scientists to develop and use an engineering approach to biology. We work closely with genomics and proteomics and collaborate with academic, research, and industry partners, including the New York Genome Center.
To apply, please contact Dr. Davoli at firstname.lastname@example.org.
Aortic Aneurysm and Platelet Biology—January 20, 2021
The laboratory of Bhama Ramkhelowan, PhD at NYU Langone Health investigates the cellular and molecular mechanisms that underly aortic aneurysms. We are expanding our team and seek a postdoctoral fellow to investigate novel immunoregulatory mechanisms in aortic aneurysms.
We collaborate with vascular surgeons to address critical unmet clinical needs in our lab, and because our research is translational, we benefit from clinical resources. Our researchers dissect mechanisms in several murine models using state-of-the-art technologies, including single-cell sequencing methods.
The postdoc is responsible for managing day-to-day lab operations, independently executing multiple experiments simultaneously over time, communicating results, and collaborating with others in the lab. You are expected to demonstrate intellectual input into the design of the project. Job responsibilities include the following:
- generating hypotheses and designs and performing experiments to test them
- recording all experimental findings in a laboratory notebook and analyzing and interpreting results
- independently suggesting and testing modifications to protocols based on results
- preparing figures and diagrams for presentations and publications
- presenting findings at lab meeting, responding to challenges, and participating in exchanges of ideas to advance the project
- reading and understanding relevant scientific literature
To qualify, you must have a PhD in the biological sciences or an MD and experience in immunobiology. Experience in platelet biology as well as excellent written and communication skills is desirable. Candidates with previous lab experience in flow cytometry and single-cell RNA sequencing, mice microsurgery skills, and a strong background in cardiovascular biology are preferred.
Please send your resume and a brief introduction to Dr. Ramkhelawon at email@example.com.