Vascular Surgery Clinical Trials

Active Clinical Trials

ANCHOR: Aneurysm Treatment using the HeliFX Aortic Securement System Global Registry

The objective is to expand the clinical knowledge base on the use of the HeliFX Aortic Securement System by including “real world” use over a broad spectrum of geographies, by a wide variety of practicing clinicians, and with a minimal degree of subject selection criteria.

Evaluation of the Zilver® Vena™ Venous Stent in the Treatment of Symptomatic Iliofemoral Venous Outflow Obstruction (VIVO Clinical Study)

The objectives of this investigation are to evaluate the safety and effectiveness of the Zilver® Vena™ Venous Stent in the treatment of symptomatic iliofemoral venous outflow obstruction.

Platelet Activity In Vascular Surgery and Cardiovascular Events (PACE)

This study seeks to understand how non-emergent, lower extremity revascularization affects different measurements of platelet activity, thrombin, coagulation and inflammatory markers, and what the association of these markers is with perioperative and long-term cardiovascular and bleeding events. (Collaborative project with Dr. Jeffrey Berger, Departments of Medicine and Surgery in the Divisions of Cardiology, Hematology, and Vascular Surgery.)

Platelet Activity and Thrombosis Registry (THoR)

The purpose of this study is to examine the relationship between risk factors for heart disease, platelet activity measurements, platelet directed therapies, and genetic information. (Collaborative project with Dr. Jeffrey Berger, Departments of Medicine and Surgery in the Divisions of Cardiology, Hematology, and Vascular Surgery.)

SeCure- A Prospective Safety and Effectiveness Study:  VenaCure Endovenous Laser Treatment (EVLT) 400 μm Fiber Procedure Kit for Treatment of Incompetent Perforator Veins

Evaluation of the safety and effectiveness of the VenaCure EVLT 400 μm Fiber Procedure Kit when used to treat Incompetent Perforator Veins (IPVs).

VIRTUS: Safety and Efficacy of the Veniti Vici™ Venous Stent System (Veniti Inc.) when Used to Treat Clinically Significant Chronic Non-malignant Obstruction of the Iliofemoral Venous Segment

Evaluation of the safety and efficacy of the Veniti Vici Venous Stent System in achieving patency of the target venous lesion in patients who present with clinically significant chronic non-malignant occlusion of the iliofemoral venous outflow tract.

Zenith® Low Profile AAA Endovascular Graft Clinical Study

Evaluation of the safety and effectiveness of the Zenith® Low Profile AAA Endovascular Graft.

Zenith® p-Branch™ Pivotal Study

Evaluation of the safety and effectiveness of the Zenith® p-Branch™ in combination with Atrium iCAST™ covered stents for the treatment of pararenal or juxtarenal aortic aneurysms.

Past Clinical Trials

A Pivotal Clinical Study to Evaluate the Safety and Effectiveness of the Ovation™ Abdominal Stent Graft System

Evaluation of the safety and efficacy of the Ovation Abdominal Stent Graft System when used in the treatment of patients with AAA.

A Randomised, Double-Blind, Parallel Group, Multicentre Phase IIIb Study to Compare Ticagrelor with Clopidogrel Treatment on the Risk of Cardiovascular Death, Myocardial Infarction and Ischaemic Stroke in Patients with Established Peripheral Artery Disease (EUCLID – Examining Use of tiCagreLor In paD)

The purpose of the study is to compare the effect of long-term treatment with ticagrelor versus clopidogrel.

A Randomized, Single-Blind, Placebo Controlled, Multicenter Study to Evaluate Efficacy and Safety of Varisolve® (polidocanol endovenous microfoam) for the Treatment of Symptomatic, Visible Varicose Veins with Saphenofemoral Junction (SFJ) Incompetence

The purpose of this study is to evaluate the effectiveness of polidocanol injectable foam in the relief of symptoms, improvement of appearance, and overall effectiveness and safety in the treatment of varicose veins compared to placebo.

Asymptomatic Carotid Stenosis, Stenting vs. Endarterectomy Trial (Act 1)

Seeks to demonstrate that carotid artery stenting using the Embosheild Cerebral Protection System with the Xact Rx Carotid Stent System is equally effective to carotid endarterectomy in treating asymptomatic extracranial carotid stenotic disease.

Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST)

The purpose of the study is to compare the relatively new procedure of stent-assisted carotid angioplasty (CAS) to the traditional and accepted surgical approach of carotid endarterectomy (CEA) for the treatment of carotid artery stenosis.

Carotid Stenting For High Surgical-Risk Patients; Evaluating Outcomes Through The Collection Of Clinical Evidence (“CHOICE”)

Post-market study of two carotid artery stent systems and two embolic protection systems.

Comparison of Safety and Primary Patency Between FUSIONTM Vascular Graft, FUSIONTM Vascular Graft with BiolinE, and EXXCELTM Soft ePTFE (FINEST)

Evaluation the safety and efficacy of the FUSION™ Vascular Graft and the FUSION™ Vascular Graft with Bioline (heparin) coating, compared with EXXCELTM.

Compression Stockings vs. No Compression Stockings after Endovenous Ablation of the Greater Saphenous Vein

Evaluation of the use of compression stockings versus no compression stockings in the perioperative management of patients undergoing endovenous ablation of their greater saphenous vein.

Endurant Stent Graft System US Clinical Study

Evaluation of the safety and effectiveness of a device to treat abdominal aortic aneurysms.

Evaluation of the Medtronic Vascular Talent Thoracic Stent Graft System for Treatment of Thoracic Aortic Aneurysms

Evaluation of patients who have had an endovascular repair of a descending thoracic aneurysm with the Talent Thoracic Stent Graft System

Evaluation of the Zilver PTX Drug-Eluting Vascular Stent in the Above-the-knee Femoropoliteal Artery

Evaluate the safety and effectiveness of the Zilver PTX Drug-Eluting Vascular Stent.

Platelet Activity in Vascular Surgery (PIVOTAL)

This study aims to evaluate both how vascular surgery affects different measurements of platelet activity and coagulation, and also the association of these markers with perioperative cardiovascular events (Collaborative project with Dr. Jeffrey Berger, Departments of Medicine and Surgery in the Divisions of Cardiology, Hematology, and Vascular Surgery).

Randomized Clinical Trial of Pneumatic Compression Device for the Treatment of Venous Ulcers and Lymphedema

Evaluation of the effect of pneumatic compression in improving symptoms, quality of life and wound healing in patients with venous ulcers and/or lymphedema.

Staple-2 Study

Evaluation of the safety and effectiveness of the Aptus Endovascular AAA Repair System for abdominal aortic aneurysms.

Study of Thoracic Aortic Aneurysm Repair with the Zenith® TX2™ TAA [Thoracic Aortic Aneurysm] Endovascular Graft

An extended investigation to continue to collect data regarding the safety and effectiveness of the Zenith TX2 TAA Endovascular Graft in the treatment of descending thoracic aortic aneurysms.

The ArterX™ Vascular Sealant Clinical Evaluation

Evaluate the safety and effectiveness of the test device, ArterX™ Vascular Sealant will be compared to the control device, Gelfoam and Thrombin.

Use of the Zenith® Dissection Endovascular System in the Treatment of Patients with Acute, Complicated Type B Aortic Dissection

Evaluation of the safety and effectiveness of the Zenith® Dissection Endovascular System in the treatment of patients with complicated, type B aortic dissection

Valor: TALENT THORACIC ENDOLUMINAL STENT GRAFT

Evaluation of a device used to treat patients with descending thoracic aneurysms of degenerative etiology who are candidates for endovascular repair.

Valor II: The Valiant Thoracic Stent Graft System Clinical Study

Evaluation of a device used to treat patients with descending thoracic aneurysms of degenerative etiology who are candidates for endovascular repair.

Zenith® Fenestrated AAA Endovascular Graft Clinical Study

Evaluation of the safety and effectiveness of the Zenith® Fenestrated AAA Endovascular Graft in the treatment of patients with abdominal aortic aneurysms (AAA) and a short infrarenal aortic neck.

Zenith® Low Profile AAA Endovascular Graft Clinical Study

Evaluation of the safety and effectiveness of the Zenith® Low Profile AAA Endovascular Graft.