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Rusk Rehabilitation Research Stroke Rehabilitation Research

Stroke Rehabilitation Research

At NYU Langone’s Rusk Rehabilitation, our research has enabled us to develop innovative therapies, devices, and technology to improve patient outcomes for people who experience a stroke.

Beginning in 2018, Jonathan H. Whiteson, MD, launched efforts to establish a research community to study the role and value of aerobic exercise in recovery and rehabilitation not only in patients with cardiopulmonary conditions but also in patients who have had stroke.

Although Rusk Rehabilitation has been integral in developing groundbreaking treatments for post-stroke muscle stiffness, Dr. Whiteson examines the effects of exercise beyond strengthening weak muscles and improving endurance after a stroke. He is examining the effects of aerobic exercise at a neurochemical and cellular level and found that it enhances the traditional rehabilitation recovery rate and provides significant cognitive benefits.

In the Mobilis Laboratory, Heidi Schambra, MD, leads a research team working to understand motor recovery after stroke and developing mechanistically informed therapies to accelerate recovery. Funded by the National Institutes of Health, the laboratory takes a multimodal approach to stud the motor system, using neurophysiological (transcranial magnetic stimulation), neuromodulatory (transcranial direct current stimulation), neuroanatomical (diffusion kurtosis MRI), biomechanical (kinematics, electromyography), and behavioral methods. This experimental approach enables the complementary appraisal of systems supporting motor learning and recovery in the upper limbs.

In the Visuomotor Integration Laboratory, John-Ross (J.R.) Rizzo, MD, MSCI, and his team focus on the intersection between ocular motor control and appendicular motor control, with a particular emphasis on understanding the mechanisms of eye–hand coordination as they relate to stroke recovery. The long-term goal of the multidisciplinary research group is to streamline the development of comprehensive diagnostics and pragmatic therapies to rapidly detect impairment and more effectively promote function. Through behavioral methodology and advanced neuroimaging, our researchers study the biomechanics of eye and hand (oculography and motion capture) to answer questions that surround visuomotor integration in motor learning and recovery.

We translate our cumulative research efforts into improved patient treatments and therapies offered through our Commission on Accreditation of Rehabilitation Facilities (CARF)–accredited stroke rehabilitation program.

Recent Publications

Feasibility and Clinician Perspectives of the Visual Symptoms and Signs Screen: A Multisite Pilot Study

Roberts, Pamela S.; Wertheimer, Jeffrey; Ouellette, Debra; Hreha, Kimberly; Watters, Kelsey; Fielder, Jaimee; Graf, Min Jeong P.; Weden, Kathleen M.; Rizzo, John Ross

Topics in geriatric rehabilitation. 2024 Jan 01; 40:69-76

Implementing Remote Patient Monitoring of Physical Activity in Clinical Practice

McCarthy, Margaret; Jevotovsky, David; Mann, Devin; Veerubhotla, Akhila; Muise, Eleanor; Whiteson, Jonathan; Rizzo, John Ross

Rehabilitation nursing. 2023 Nov-Dec 01; 48:209-215

Disparities in Breast Cancer Patients with Disabilities: Care Gaps, Accessibility, and Best Practices

Keegan, Grace; Rizzo, John-Ross; Joseph, Kathie-Ann

Journal of the National Cancer Institute. 2023 Oct 09; 115:1139-1144

Pulmonary Sequelae of Coronavirus Disease 2019

Whiteson, Jonathan H

Physical medicine & rehabilitation clinics of North America. 2023 Aug ; 34:573-584

Methodological Issues Relevant to Blinding in Physical Medicine and Rehabilitation Research

Annaswamy, Thiru; Cunniff, Kegan; Rizzo, J R; Naeimi, Tahereh; Kumbhare, Dinesh; Batavia, Mitchell

American journal of physical medicine & rehabilitation. 2023 Jul 01; 102:636-644

Virtual reality as a means to explore assistive technologies for the visually impaired

Ricci, Fabiana Sofia; Boldini, Alain; Ma, Xinda; Beheshti, Mahya; Geruschat, Duane R; Seiple, William H; Rizzo, John-Ross; Porfiri, Maurizio

PLOS digital health. 2023 Jun ; 2:e0000275

Data-Driven Quantitation of Movement Abnormality after Stroke

Parnandi, Avinash; Kaku, Aakash; Venkatesan, Anita; Pandit, Natasha; Fokas, Emily; Yu, Boyang; Kim, Grace; Nilsen, Dawn; Fernandez-Granda, Carlos; Schambra, Heidi

Bioengineering. 2023 May 26; 10:

Association of Brain Age, Lesion Volume, and Functional Outcome in Patients With Stroke

Liew, Sook-Lei; Schweighofer, Nicolas; Cole, James H; Zavaliangos-Petropulu, Artemis; Lo, Bethany P; Han, Laura K M; Hahn, Tim; Schmaal, Lianne; Donnelly, Miranda R; Jeong, Jessica N; Wang, Zhizhuo; Abdullah, Aisha; Kim, Jun H; Hutton, Alexandre; Barisano, Giuseppe; Borich, Michael R; Boyd, Lara A; Brodtmann, Amy; Buetefisch, Cathrin M; Byblow, Winston D; Cassidy, Jessica M; Charalambous, Charalambos C; Ciullo, Valentina; Conforto, Adriana Bastos; Dacosta-Aguayo, Rosalia; DiCarlo, Julie A; Domin, Martin; Dula, Adrienne N; Egorova-Brumley, Natalia; Feng, Wuwei; Geranmayeh, Fatemeh; Gregory, Chris M; Hanlon, Colleen A; Hayward, Kathryn; Holguin, Jess A; Hordacre, Brenton; Jahanshad, Neda; Kautz, Steven A; Khlif, Mohamed Salah; Kim, Hosung; Kuceyeski, Amy; Lin, David J; Liu, Jingchun; Lotze, Martin; MacIntosh, Bradley J; Margetis, John L; Mataro, Maria; Mohamed, Feroze B; Olafson, Emily R; Park, Gilsoon; Piras, Fabrizio; Revill, Kate P; Roberts, Pamela; Robertson, Andrew D; Sanossian, Nerses; Schambra, Heidi M; Seo, Na Jin; Soekadar, Surjo R; Spalletta, Gianfranco; Stinear, Cathy M; Taga, Myriam; Tang, Wai Kwong; Thielman, Greg T; Vecchio, Daniela; Ward, Nick S; Westlye, Lars T; Winstein, Carolee J; Wittenberg, George F; Wolf, Steven L; Wong, Kristin A; Yu, Chunshui; Cramer, Steven C; Thompson, Paul M

Neurology. 2023 May 16; 100:e2103-e2113