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Rusk Rehabilitation Research Stroke Rehabilitation Research

Stroke Rehabilitation Research

At NYU Langone’s Rusk Rehabilitation, our research has enabled us to develop innovative therapies, devices, and technology to improve patient outcomes for people who experience a stroke.

Beginning in 2018, Jonathan H. Whiteson, MD, launched efforts to establish a research community to study the role and value of aerobic exercise in recovery and rehabilitation not only in patients with cardiopulmonary conditions but also in patients who have had stroke.

Although Rusk Rehabilitation has been integral in developing groundbreaking treatments for post-stroke muscle stiffness, Dr. Whiteson examines the effects of exercise beyond strengthening weak muscles and improving endurance after a stroke. He is examining the effects of aerobic exercise at a neurochemical and cellular level and found that it enhances the traditional rehabilitation recovery rate and provides significant cognitive benefits.

In the Mobilis Laboratory, Heidi Schambra, MD, leads a research team working to understand motor recovery after stroke and developing mechanistically informed therapies to accelerate recovery. Funded by the National Institutes of Health, the laboratory takes a multimodal approach to stud the motor system, using neurophysiological (transcranial magnetic stimulation), neuromodulatory (transcranial direct current stimulation), neuroanatomical (diffusion kurtosis MRI), biomechanical (kinematics, electromyography), and behavioral methods. This experimental approach enables the complementary appraisal of systems supporting motor learning and recovery in the upper limbs.

In the Visuomotor Integration Laboratory, John-Ross (J.R.) Rizzo, MD, MSCI, and his team focus on the intersection between ocular motor control and appendicular motor control, with a particular emphasis on understanding the mechanisms of eye–hand coordination as they relate to stroke recovery. The long-term goal of the multidisciplinary research group is to streamline the development of comprehensive diagnostics and pragmatic therapies to rapidly detect impairment and more effectively promote function. Through behavioral methodology and advanced neuroimaging, our researchers study the biomechanics of eye and hand (oculography and motion capture) to answer questions that surround visuomotor integration in motor learning and recovery.

We translate our cumulative research efforts into improved patient treatments and therapies offered through our Commission on Accreditation of Rehabilitation Facilities (CARF)–accredited stroke rehabilitation program.

Recent Publications

Evidence-Based Medicine Training in US-based Physiatry Residency Programs

Annaswamy, Thiru M; Rizzo, John-Ross; Schnappinger, Amy; Morgenroth, David C; Engkasan, Julia Patrick; Ilieva, Elena; Arnold, W David; Boninger, Mike; Bean, Allison C; Cirstea, Carmen M; Dicianno, Brad E; Fredericson, Michael; Jayabalan, Prakash; Raghavan, Preeti; Sawaki, Lumy; Suri, Pradeep; Suskauer, Stacy J; Wang, Qing Mei; Hosseini, Maryam; Case, Christina; Whyte, John; Paganoni, Sabrina

American journal of physical medicine & rehabilitation. 2022 Jul 01; 101:S40-S44

Let's Write a Manuscript - A Primer with Tips & Tricks for Penning an Original Article

Ozcakar, Levent; Rizzo, John-Ross; Franchignoni, Franco; Negrini, Stefano; Frontera, Walter R

American journal of physical medicine & rehabilitation. 2022 Jul 01; 101:698-701

Multi-Disciplinary Collaborative Consensus Guidance Statement on the Assessment and Treatment of Cardiovascular Complications in Patients with Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)

Whiteson, Jonathan; Azola, Alba; Barry, John T; Bartels, Matthew N; Blitshteyn, Svetlana; Fleming, Talya K; McCauley, Mark D; Neal, Jacqueline D; Pillarisetti, Jayasree; Sampsel, Sarah; Silver, Julie K; Terzic, Carmen M; Tosto, Jenna; Verduzco-Gutierrez, Monica; Putrino, David

PM&R. 2022 Jun 03;

Chronic Stroke Sensorimotor Impairment Is Related to Smaller Hippocampal Volumes: An ENIGMA Analysis

Zavaliangos-Petropulu, Artemis; Lo, Bethany; Donnelly, Miranda R; Schweighofer, Nicolas; Lohse, Keith; Jahanshad, Neda; Barisano, Giuseppe; Banaj, Nerisa; Borich, Michael R; Boyd, Lara A; Buetefisch, Cathrin M; Byblow, Winston D; Cassidy, Jessica M; Charalambous, Charalambos C; Conforto, Adriana B; DiCarlo, Julie A; Dula, Adrienne N; Egorova-Brumley, Natalia; Etherton, Mark R; Feng, Wuwei; Fercho, Kelene A; Geranmayeh, Fatemeh; Hanlon, Colleen A; Hayward, Kathryn S; Hordacre, Brenton; Kautz, Steven A; Khlif, Mohamed Salah; Kim, Hosung; Kuceyeski, Amy; Lin, David J; Liu, Jingchun; Lotze, Martin; MacIntosh, Bradley J; Margetis, John L; Mohamed, Feroze B; Piras, Fabrizio; Ramos-Murguialday, Ander; Revill, Kate P; Roberts, Pamela S; Robertson, Andrew D; Schambra, Heidi M; Seo, Na Jin; Shiroishi, Mark S; Stinear, Cathy M; Soekadar, Surjo R; Spalletta, Gianfranco; Taga, Myriam; Tang, Wai Kwong; Thielman, Gregory T; Vecchio, Daniela; Ward, Nick S; Westlye, Lars T; Werden, Emilio; Winstein, Carolee; Wittenberg, George F; Wolf, Steven L; Wong, Kristin A; Yu, Chunshui; Brodtmann, Amy; Cramer, Steven C; Thompson, Paul M; Liew, Sook-Lei

Journal of the American Heart Association. 2022 May 17; 11:e025109

Rehabilitation Using Mobile Health for Older Adults With Ischemic Heart Disease in the Home Setting (RESILIENT): Protocol for a Randomized Controlled Trial

Dodson, John A; Schoenthaler, Antoinette; Sweeney, Greg; Fonceva, Ana; Pierre, Alicia; Whiteson, Jonathan; George, Barbara; Marzo, Kevin; Drewes, Wendy; Rerisi, Elizabeth; Mathew, Reena; Aljayyousi, Haneen; Chaudhry, Sarwat I; Hajduk, Alexandra M; Gill, Thomas M; Estrin, Deborah; Kovell, Lara; Jennings, Lee A; Adhikari, Samrachana

JMIR research protocols. 2022 Mar 03; 11:e32163

The MICK (Mobile integrated cognitive kit) app: Digital rapid automatized naming for visual assessment across the spectrum of neurological disorders

Park, George; Balcer, Marc J; Hasanaj, Lisena; Joseph, Binu; Kenney, Rachel; Hudson, Todd; Rizzo, John-Ross; Rucker, Janet C; Galetta, Steven L; Balcer, Laura J; Grossman, Scott N

Journal of the neurological sciences. 2022 Jan 11; 434:120150

Network-Aware 5G Edge Computing for Object Detection: Augmenting Wearables to “See” More, Farther and Faster

Yuan, Zhongzheng; Azzino, Tommy; Hao, Yu; Lyu, Yixuan; Pei, Haoyang; Boldini, Alain; Mezzavilla, Marco; Beheshti, Mahya; Porfiri, Maurizio; Hudson, Todd; Seiple, William; Fang, Yi; Rangan, Sundeep; Wang, Yao; Rizzo, J. R.

IEEE access : practical innovations, open solutions. 2022 Jan 01; ?-?

Multi-Disciplinary Collaborative Consensus Guidance Statement on the Assessment and Treatment of Breathing Discomfort and Respiratory Sequelae in Patients with Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)

Maley, Jason H; Alba, George A; Barry, John T; Bartels, Matthew N; Fleming, Talya K; Oleson, Christina V; Rydberg, Leslie; Sampsel, Sarah; Silver, Julie K; Sipes, Sabrina; Verduzco Gutierrez, Monica; Wood, Jamie; Zibrak, Joseph D; Whiteson, Jonathan

PM&R. 2022 Jan ; 14:77-95