Clinical Trials and Research Professionals

Hassenfeld is dedicated to finding new ways to prevent and treat cancer. One way we do this is by participating in clinical trials research. Hassenfeld’s clinical trials staff consists of a Principal Investigator (PI) and Clinical Research Associates (CRA).

Principal Investigator

The principal investigator (PI) has primary responsibility for the overall conduct of the clinical trial, while also complying with the financial and administrative policies and regulations associated with project.

Although PIs may have administrative staff to assist them, the ultimate responsibility for the management of the project rests with the PI.

The PI is responsible for reviewing clinical trial protocols and the consent forms with participating patients and their families. The PI will answer any questions regarding the study.

Clinical Research Associates

Clinical Research Associates (CRA) contribute to research studies that have a major impact on health care, such as developing new medications and testing new treatment methods.

Significant advancements in these areas and expanding regulatory requirements have increased the demand for trained CRAs.

The role of the CRA is to assist in the design, preparation, planning, implementation and review of a clinical trial to ensure it adheres to regulatory and ethical standards.

The CRA ensures compliance with study protocol, applicable regulations, Good Clinical Practices (GCP), FDA Regulatory requirements, and overall clinical objectives.

Responsibilities of the CRA include managing the initiation of clinical trials according to regulatory and institutional guidelines and requirements; registering and enrolling eligible patients; extracting, compiling, evaluating and submitting data; monitoring study compliance; monitoring and maintaining on-going regulatory requirements; providing information and feedback on designated clinical trials; and coordinating the data management systems.

Laboratory Researchers

Breakthroughs in understanding the causes of childhood cancer and blood disorders take place in our basic research laboratories and our doctors are “translating” these breakthroughs into better treatments for children.

Our team of researchers conducts “translational” research in the Pediatric Leukemia Research Laboratory.

The lab, headed by Dr. William Carroll, is at the brand-new Smilow Research Center on First Avenue.

The researchers carry out experiments to find new methods of better, more “personalized” treatments with fewer side effects.

Using the latest DNA technology, this research team analyzes tissue samples from patients enrolled in clinical trials to understand the changes that cause cancer cell death.