Center Expands Eye Research Program

In recent years we’ve focused our research efforts on understanding the visual problems in familial dysautonomia (FD). The work of Dr. Carlos Mendoza, a neuro-opthalmologist trained in Cuba and at Tuffs University (Boston) has reshaped the way we understand visual loss in FD. Dr. Mendoza showed that patients with FD have a progressive degeneration of the optic nerve and loss of fibers in the retina, a similar pattern to that of mitochondrial optic neuropathies.


Thanks to the funding of the Dysautonomia Foundation, Inc. we were able to expand our eye research program at the Center. We now have a state of the art laboratory to examine the innervation of the eye and visual function. We are continuing to study the eye in FD and have begun studies to understand the involvement of the eye in other neurological diseases that are associated with autonomic dysfunction. 

See publications from the Center on the eye in familial dysautonomia:

Mendoza-Santiesteban CE, Hedges TR 3rd, Norcliffe-Kaufmann L, Warren F, Reddy S, Axelrod FB, Kaufmann H. Clinical neuro-ophthalmic findings in familial dysautonomia. J Neuroophthalmol. 2012 Mar;32(1):23-6.

Find out more about research projects involving the eye ongoing at the Center:

The Eye in Familial Dysautonomia (longitudinal study)
The Eye in Neurodegenerative Diseases

Learn more about Dr. Mendoza here >>