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Rusk Rehabilitation Research Stroke Rehabilitation Research

Stroke Rehabilitation Research

At NYU Langone’s Rusk Rehabilitation, our research has enabled us to develop innovative therapies, devices, and technology to improve patient outcomes for people who experience a stroke.

Beginning in 2018, Jonathan H. Whiteson, MD, launched efforts to establish a research community to study the role and value of aerobic exercise in recovery and rehabilitation not only in patients with cardiopulmonary conditions but also in patients who have had stroke.

Although Rusk Rehabilitation has been integral in developing groundbreaking treatments for post-stroke muscle stiffness, Dr. Whiteson examines the effects of exercise beyond strengthening weak muscles and improving endurance after a stroke. He is examining the effects of aerobic exercise at a neurochemical and cellular level and found that it enhances the traditional rehabilitation recovery rate and provides significant cognitive benefits.

In the Mobilis Laboratory, Heidi Schambra, MD, leads a research team working to understand motor recovery after stroke and developing mechanistically informed therapies to accelerate recovery. Funded by the National Institutes of Health, the laboratory takes a multimodal approach to stud the motor system, using neurophysiological (transcranial magnetic stimulation), neuromodulatory (transcranial direct current stimulation), neuroanatomical (diffusion kurtosis MRI), biomechanical (kinematics, electromyography), and behavioral methods. This experimental approach enables the complementary appraisal of systems supporting motor learning and recovery in the upper limbs.

In the Visuomotor Integration Laboratory, John-Ross (J.R.) Rizzo, MD, MSCI, and his team focus on the intersection between ocular motor control and appendicular motor control, with a particular emphasis on understanding the mechanisms of eye–hand coordination as they relate to stroke recovery. The long-term goal of the multidisciplinary research group is to streamline the development of comprehensive diagnostics and pragmatic therapies to rapidly detect impairment and more effectively promote function. Through behavioral methodology and advanced neuroimaging, our researchers study the biomechanics of eye and hand (oculography and motion capture) to answer questions that surround visuomotor integration in motor learning and recovery.

We translate our cumulative research efforts into improved patient treatments and therapies offered through our Commission on Accreditation of Rehabilitation Facilities (CARF)–accredited stroke rehabilitation program.

Recent Publications

Quantifying impairment and disease severity using AI models trained on healthy subjects

Yu, Boyang; Kaku, Aakash; Liu, Kangning; Parnandi, Avinash; Fokas, Emily; Venkatesan, Anita; Pandit, Natasha; Ranganath, Rajesh; Schambra, Heidi; Fernandez-Granda, Carlos

npj Digital Medicine. 2024 Dec 01; 7:?-?

Vagus nerve stimulation for stroke rehabilitation: Neural substrates, neuromodulatory effects and therapeutic implications

Schambra, Heidi M; Hays, Seth A

Journal of physiology. 2024 Sep 07;

Curricula for training advanced practice providers as part of the physiatrist-led team

Burris, Joseph E; Alm, John C; Gershon, Steven L; Kim, Heakyung; Russo, David P; Smith, Charlotte H; Vincent, Kevin R; Whiteson, Jonathan H

PM & R : the journal of injury, function, and rehabilitation. 2024 Jul ; 16:766-768

Improvisation and live accompaniment increase motor response and reward during a music playing task

Palumbo, Anna; Groves, Karleigh; Munoz-Vidal, Eva Luna; Turry, Alan; Codio, Robert; Raghavan, Preeti; Schambra, Heidi; Voelbel, Gerald T; Ripollés, Pablo

Scientific reports. 2024 Jun 07; 14:13112

A Multi-Modal Foundation Model to Assist People with Blindness and Low Vision in Environmental Interaction

Hao, Yu; Yang, Fan; Huang, Hao; Yuan, Shuaihang; Rangan, Sundeep; Rizzo, John Ross; Wang, Yao; Fang, Yi

Journal of imaging. 2024 May 01; 10:?-?

A Multi-Modal Foundation Model to Assist People with Blindness and Low Vision in Environmental Interaction

Hao, Yu; Yang, Fan; Huang, Hao; Yuan, Shuaihang; Rangan, Sundeep; Rizzo, John-Ross; Wang, Yao; Fang, Yi

Journal of imaging. 2024 Apr 26; 10:

Feasibility and Clinician Perspectives of the Visual Symptoms and Signs Screen: A Multisite Pilot Study

Roberts, Pamela S.; Wertheimer, Jeffrey; Ouellette, Debra; Hreha, Kimberly; Watters, Kelsey; Fielder, Jaimee; Graf, Min Jeong P.; Weden, Kathleen M.; Rizzo, John Ross

Topics in geriatric rehabilitation. 2024 Jan 01; 40:69-76

Accuracy and Usability of Smartphone-Based Distance Estimation Approaches for Visual Assistive Technology Development

Hamilton-Fletcher, Giles; Liu, Mingxin; Sheng, Diwei; Feng, Chen; Hudson, Todd E.; Rizzo, John Ross; Chan, Kevin C.

IEEE Open Journal of Engineering in Medicine and Biology. 2024 Jan 01; 5:54-58