Stroke Rehabilitation Research
At NYU Langone’s Rusk Rehabilitation, our research has enabled us to develop innovative therapies, devices, and technology to improve patient outcomes for people who experience a stroke.
Beginning in 2018, Jonathan H. Whiteson, MD, launched efforts to establish a research community to study the role and value of aerobic exercise in recovery and rehabilitation not only in patients with cardiopulmonary conditions but also in patients who have had stroke.
Although Rusk Rehabilitation has been integral in developing groundbreaking treatments for post-stroke muscle stiffness, Dr. Whiteson examines the effects of exercise beyond strengthening weak muscles and improving endurance after a stroke. He is examining the effects of aerobic exercise at a neurochemical and cellular level and found that it enhances the traditional rehabilitation recovery rate and provides significant cognitive benefits.
In the Mobilis Laboratory, Heidi Schambra, MD, leads a research team working to understand motor recovery after stroke and developing mechanistically informed therapies to accelerate recovery. Funded by the National Institutes of Health, the laboratory takes a multimodal approach to stud the motor system, using neurophysiological (transcranial magnetic stimulation), neuromodulatory (transcranial direct current stimulation), neuroanatomical (diffusion kurtosis MRI), biomechanical (kinematics, electromyography), and behavioral methods. This experimental approach enables the complementary appraisal of systems supporting motor learning and recovery in the upper limbs.
In the Visuomotor Integration Laboratory, John-Ross (J.R.) Rizzo, MD, MSCI, and his team focus on the intersection between ocular motor control and appendicular motor control, with a particular emphasis on understanding the mechanisms of eye–hand coordination as they relate to stroke recovery. The long-term goal of the multidisciplinary research group is to streamline the development of comprehensive diagnostics and pragmatic therapies to rapidly detect impairment and more effectively promote function. Through behavioral methodology and advanced neuroimaging, our researchers study the biomechanics of eye and hand (oculography and motion capture) to answer questions that surround visuomotor integration in motor learning and recovery.
We translate our cumulative research efforts into improved patient treatments and therapies offered through our Commission on Accreditation of Rehabilitation Facilities (CARF)–accredited stroke rehabilitation program.
Recent Publications
Reducing barriers through education: A scoping review calling for structured disability curricula in surgical training programs
American journal of surgery. 2025 Jan ; 239:116062
Corticospinal and corticoreticulospinal projections have discrete but complementary roles in chronic motor behaviors after stroke
Journal of neurophysiology. 2024 Dec 01; 132:1917-1936
Navigation Training for Persons With Visual Disability Through Multisensory Assistive Technology: Mixed Methods Experimental Study
JMIR rehabilitation & assistive technologies. 2024 Nov 18; 11:e55776
The criticality of reasonable accommodations: A scoping review revealing gaps in care for patients with blindness and low vision
American journal of surgery. 2024 Nov 13; 241:116085
Examining Risk Factors Related to Cardiac Rehabilitation Cessation Among Patients With Advanced Heart Failure
Journal of cardiopulmonary rehabilitation & prevention. 2024 Oct 29;
Vagus nerve stimulation for stroke rehabilitation: Neural substrates, neuromodulatory effects and therapeutic implications
Journal of physiology. 2024 Sep 07;
Evaluating the efficacy of UNav: A computer vision-based navigation aid for persons with blindness or low vision
Assistive technology. 2024 Aug 13; 1-15
Quantifying impairment and disease severity using AI models trained on healthy subjects
NPJ digital medicine. 2024 Jul 06; 7:180