
Pediatric Pulmonary Medicine Research
NYU Langone’s Division of Pediatric Pulmonary Medicine is at the forefront of clinical research, aiming always to advance understanding of and treatments for pulmonary diseases in children.
The division is participating in an original study of the microbiome of the respiratory and gastrointestinal tracts to determine whether bacteria that live in the airway change with disease. Working in conjunction with the Division of Pulmonary, Critical Care, and Sleep Medicine, researchers have studied the microbiome in pediatric patients with chronic cough, determining that the lower-airway microbiota in these patients is affected by microbial continuity between different mucosae and distinct dysbiotic signatures.
In addition, research collaborations between NYU Langone’s Pediatric Cystic Fibrosis Center and the Cystic Fibrosis Foundation have led to improvements in quality of life and longevity for people with the condition.
Research efforts are directed toward management of severe uncontrolled asthma in children. Investigators in the division have discovered that aerodigestive eosinophils are frequently present in children who have severe uncontrolled asthma, suggesting that aerodigestive eosinophilic inflammation may be a factor to consider in management of the disease.
As a Primary Ciliary Dyskinesia Center, division members are conducting a research-based evaluation of the use of nasal nitric oxide to diagnose pulmonary disease in children over the age of 5.
Recent Publications
Characterization of 223 infants with CFTR-related metabolic syndrome/Cystic fibrosis screen positive, inconclusive diagnosis (CRMS/CFSPID) identified during the first three years of newborn screening via IRT-DNA-SEQ in New York State
Journal of cystic fibrosis. 2024 Nov 11;
Characterization of 223 infants with CFTR-related metabolic syndrome/Cystic fibrosis screen positive, inconclusive diagnosis (CRMS/CFSPID) identified during the first three years of newborn screening via IRT-DNA-SEQ in New York State
Journal of cystic fibrosis. 2024 Nov 11;
New York cystic fibrosis consortium newborn screening quality improvement: Development and implementation of a statewide consensus recommendations for management of infants with CFTR-related metabolic syndrome
Pediatric pulmonology. 2024 Nov ; 59:2932-2938
Genetic counseling access and service delivery in New York State is variable for parents of infants with complex CFTR genotypes conferring uncertain phenotypes
Pediatric pulmonology. 2024 Jul ; 59:1952-1961
The clinical impact of the Covid-19 pandemic first wave on patients with cystic fibrosis in New York
Journal of cystic fibrosis. 2022 May ; 21:e176-e183
80 New York Cystic Fibrosis Newborn Screening Consortium quality improvement: Focus on parent and pediatrician education and development of a statewide standard of care for CF-related metabolic syndrome infants
Journal of cystic fibrosis. 2021 November; 20:S40
Approach to patient with cough by American and Chinese respiratory specialist
Complementary therapies in medicine. 2021 May 25; 102733
Pulmonary Manifestations of Renal Disorders in Children
Pediatric clinics of North America. 2021 Feb ; 68:209-222