Pediatric Pulmonary Medicine Research | NYU Langone Health

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Division of Pediatric Pulmonary Medicine Pediatric Pulmonary Medicine Research

Pediatric Pulmonary Medicine Research

NYU Langone’s Division of Pediatric Pulmonary Medicine is at the forefront of clinical research, aiming always to advance understanding of and treatments for pulmonary diseases in children.

The division is participating in an original study of the microbiome of the respiratory and gastrointestinal tracts to determine whether bacteria that live in the airway change with disease. Working in conjunction with the Division of Pulmonary, Critical Care, and Sleep Medicine, researchers have studied the microbiome in pediatric patients with chronic cough, determining that the lower-airway microbiota in these patients is affected by microbial continuity between different mucosae and distinct dysbiotic signatures.

In addition, research collaborations between NYU Langone’s Pediatric Cystic Fibrosis Center and the Cystic Fibrosis Foundation have led to improvements in quality of life and longevity for people with the condition.

Research efforts are directed toward management of severe uncontrolled asthma in children. Investigators in the division have discovered that aerodigestive eosinophils are frequently present in children who have severe uncontrolled asthma, suggesting that aerodigestive eosinophilic inflammation may be a factor to consider in management of the disease.

As a Primary Ciliary Dyskinesia Center, division members are conducting a research-based evaluation of the use of nasal nitric oxide to diagnose pulmonary disease in children over the age of 5.

Recent Publications

The clinical impact of the Covid-19 pandemic first wave on patients with cystic fibrosis in New York

Simonson, Joseph L; Esposito, Christine; Frantzen, Theresa; Henthorne, Katherine; Espinal, Aileen; Romano, Serena; Ramdeo, Ramona; Trentacoste, Jessica; Tsang, Donna; LaVecchia, Geralyn; Abdullah, Robert; Berdella, Maria; Bonitz, Lynn; Condos, Rany; Constantinescu, Andrei; DeCelie-Germana, Joan K; DiMango, Emily; Draine, Myah; Gimeli, Tara; Giusti, Robert; Guzman, Jessenia; Hammouda, Soumia; Keating, Claire; Kier, Catherine; Lennox, Alison T; Liriano, Carmen; Messer, Zachary; Plachta, Amy; Sadeghi, Hossein; Schwind, Elinor; Stables-Carney, Teresa; Walker, Patricia; Wang, Janice

Journal of cystic fibrosis. 2022 May ; 21:e176-e183

80 New York Cystic Fibrosis Newborn Screening Consortium quality improvement: Focus on parent and pediatrician education and development of a statewide standard of care for CF-related metabolic syndrome infants

Choudhary, S; Giusti, R; Goetz, D; Kaslovsky, R; Berdella, M; Sadeghi, H; DeCelie-Germana, J; Welter, J; Kier, C; Fortner, C; Voter, K; Kay, D; Hammouda, S

Journal of cystic fibrosis. 2021 November; 20:S40

Approach to patient with cough by American and Chinese respiratory specialist

Liu, Xiuxiu; Kesebir, Deniz; Kazachkov, Mikhail

Complementary therapies in medicine. 2021 May 25; 102733

Pulmonary Manifestations of Renal Disorders in Children

Malaga-Dieguez, Laura; Trachtman, Howard; Giusti, Robert

Pediatric clinics of North America. 2021 Feb ; 68:209-222

Diagnosis of EVALI in the COVID-19 era

Kazachkov, Mikhail; Pirzada, Melodi

Lancet. Respiratory medicine. 2020 Dec ; 8:1169-1170

Airway manifestations of sarcoidosis in adolescents

Obsekov, Vladislav; Chen, Linda; Pirzada, Melodi; Giusti, Robert; Kazachkov, Mikhail

Pediatric pulmonology. 2020 Oct ; 55:2742-2744

Care recommendations for the respiratory complications of esophageal atresia-tracheoesophageal fistula

Koumbourlis, Anastassios C; Belessis, Yvonne; Cataletto, Mary; Cutrera, Renato; DeBoer, Emily; Kazachkov, Mikhail; Laberge, Sophie; Popler, Jonathan; Porcaro, Federica; Kovesi, Thomas

Pediatric pulmonology. 2020 Oct ; 55:2713-2729

The roles of a pediatric pulmonologist during the COVID-19 pandemic

Kazachkov, Mikhail; Noah, Terry L; Murphy, Thomas M

Pediatric pulmonology. 2020 Oct ; 55:2592-2595