Pediatric Rheumatology Research | NYU Langone Health

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Division of Pediatric Rheumatology Pediatric Rheumatology Research

Pediatric Rheumatology Research

The Division of Pediatric Rheumatology at NYU Langone participates in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry to help develop a database for childhood rheumatic diseases such as juvenile idiopathic arthritis, dermatomyositis, and systemic lupus erythematosus. The registry illustrates the feasibility of using data-intensive registries for observational studies, comparative research, translational research, and clinical trials.

Division investigators have collaborated with CARRA in research pertaining to the development of consensus treatment protocols for dermatomyositis. The division has also collaborated in the assessment of skin disease in patients with lupus and dermatomyositis, as well as validating current skin scoring tools in pediatrics.

Future translational research projects include studies of type 1 interferon and toll-like receptor pathways in understanding differences in treatment response in inflammatory arthritis.

Recent Publications

Intravenous Anakinra for Macrophage Activation Syndrome May Hold Lessons for Treatment of Cytokine Storm in the Setting of Coronavirus Disease 2019

Wampler Muskardin, Theresa L

ACR open rheumatology. 2020 May ; 2:283-285

Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases

de Jesus, Adriana A; Hou, Yangfeng; Brooks, Stephen; Malle, Louise; Biancotto, Angelique; Huang, Yan; Calvo, Katherine R; Marrero, Bernadette; Moir, Susan; Oler, Andrew J; Deng, Zuoming; Montealegre Sanchez, Gina A; Ahmed, Amina; Allenspach, Eric; Arabshahi, Bita; Behrens, Edward; Benseler, Susanne; Bezrodnik, Liliana; Bout-Tabaku, Sharon; Brescia, AnneMarie C; Brown, Diane; Burnham, Jon M; Caldirola, Maria Soledad; Carrasco, Ruy; Chan, Alice Y; Cimaz, Rolando; Dancey, Paul; Dare, Jason; DeGuzman, Marietta; Dimitriades, Victoria; Ferguson, Ian; Ferguson, Polly; Finn, Laura; Gattorno, Marco; Grom, Alexei A; Hanson, Eric P; Hashkes, Philip J; Hedrich, Christian M; Herzog, Ronit; Horneff, Gerd; Jerath, Rita; Kessler, Elizabeth; Kim, Hanna; Kingsbury, Daniel J; Laxer, Ronald M; Lee, Pui Y; Lee-Kirsch, Min Ae; Lewandowski, Laura; Li, Suzanne; Lilleby, Vibke; Mammadova, Vafa; Moorthy, Lakshmi N; Nasrullayeva, Gulnara; O'Neil, Kathleen M; Onel, Karen; Ozen, Seza; Pan, Nancy; Pillet, Pascal; Piotto, Daniela Gp; Punaro, Marilynn G; Reiff, Andreas; Reinhardt, Adam; Rider, Lisa G; Rivas-Chacon, Rafael; Ronis, Tova; Rösen-Wolff, Angela; Roth, Johannes; Ruth, Natasha Mckerran; Rygg, Marite; Schmeling, Heinrike; Schulert, Grant; Scott, Christiaan; Seminario, Gisella; Shulman, Andrew; Sivaraman, Vidya; Son, Mary Beth; Stepanovskiy, Yuriy; Stringer, Elizabeth; Taber, Sara; Terreri, Maria Teresa; Tifft, Cynthia; Torgerson, Troy; Tosi, Laura; Van Royen-Kerkhof, Annet; Wampler Muskardin, Theresa; Canna, Scott W; Goldbach-Mansky, Raphaela

Journal of clinical investigation. 2020 Apr 01; 130:1669-1682

Lessons from precision medicine in rheumatology

Wampler Muskardin, Theresa L; Paredes, Jacqueline L; Appenzeller, Simone; Niewold, Timothy B

Multiple sclerosis. 2020 Jan 22; 1352458519884249

Interferon Chemokine Score and Other Cytokine Measures Track With Changes in Disease Activity in Patients With Juvenile and Adult Dermatomyositis

Crowson, Cynthia S; Hein, Molly S; Pendegraft, Richard S; Strausbauch, Michael A; Niewold, Timothy B; Ernste, Floranne C; Dvergsten, Jeffrey; Amin, Shreyasee; Wampler Muskardin, Theresa L; Peterson, Erik; Baechler, Emily C; Reed, Ann M

ACR open rheumatology. 2019 Apr ; 1:83-89

Evaluation of the reliability and validity of the Cutaneous Lupus Erythematosus Disease Area and Severity Index (CLASI) in pediatric cutaneous lupus among pediatric dermatologists and rheumatologists

Kushner, C J; Tarazi, M; Gaffney, R G; Feng, R; Ardalan, K; Brandling-Bennett, H A; Castelo-Soccio, L; Chang, J C; Chiu, Y E; Gmuca, S; Hunt, R D; Kahn, P J; Knight, A M; Mehta, J; Pearson, D R; Treat, J R; Wan, J; Yeguez, A C; Concha, J S S; Patel, B; Okawa, J; Arkin, L M; Werth, V P

British journal of dermatology. 2019 Jan ; 180:165-171

Comparing the importance of quality measurement themes in juvenile idiopathic inflammatory myositis between patients and families and healthcare professionals

Tory, Heather O; Carrasco, Ruy; Griffin, Thomas; Huber, Adam M; Kahn, Philip; Robinson, Angela Byun; Zurakowski, David; Kim, Susan

Pediatric rheumatology online journal. 2018 Apr 19; 16:28

A Novel ELANE Mutation Associated with Inflammatory Arthritis, Defective NETosis, and Recurrent Parvoviral Infection

Thanarajasingam, Uma; Jensen, Mark A; Dorschner, Jessica M; Wampler Muskardin, Theresa; Ghodke-Puranik, Yogita; Purmalek, Monica; Eliopoulos, Elias; Zervou, Maria I; Goulielmos, George N; Howard, Matthew; Kaplan, Mariana J; Niewold, Timothy B

Arthritis & rheumatology. 2017 12 ; 69:2396-2401

Patient-provider discordance between global assessments of disease activity in rheumatoid arthritis: a comprehensive clinical evaluation

Challa, Divya N; Kvrgic, Zoran; Cheville, Andrea L; Crowson, Cynthia S; Bongartz, Tim; Mason, Thomas G; Matteson, Eric L; Michet, Clement J; Persellin, Scott T; Schaffer, Daniel E; Muskardin, Theresa L Wampler; Wright, Kerry; Davis, John M

Arthritis research & therapy. 2017 09 26; 19:212