Pediatric Rheumatology Research
The Division of Pediatric Rheumatology at NYU Langone participates in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry to help develop a database for childhood rheumatic diseases such as juvenile idiopathic arthritis, dermatomyositis, and systemic lupus erythematosus. The registry illustrates the feasibility of using data-intensive registries for observational studies, comparative research, translational research, and clinical trials.
Division investigators have collaborated with CARRA in research pertaining to the development of consensus treatment protocols for dermatomyositis. The division has also collaborated in the assessment of skin disease in patients with lupus and dermatomyositis, as well as validating current skin scoring tools in pediatrics.
Future translational research projects include studies of type 1 interferon and toll-like receptor pathways in understanding differences in treatment response in inflammatory arthritis.
Intravenous Anakinra for Macrophage Activation Syndrome May Hold Lessons for Treatment of Cytokine Storm in the Setting of Coronavirus Disease 2019
ACR open rheumatology. 2020 May ; 2:283-285
Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases
Journal of clinical investigation. 2020 Apr 01; 130:1669-1682
Lessons from precision medicine in rheumatology
Multiple sclerosis. 2020 Jan 22; 1352458519884249
Interferon Chemokine Score and Other Cytokine Measures Track With Changes in Disease Activity in Patients With Juvenile and Adult Dermatomyositis
ACR open rheumatology. 2019 Apr ; 1:83-89
Evaluation of the reliability and validity of the Cutaneous Lupus Erythematosus Disease Area and Severity Index (CLASI) in pediatric cutaneous lupus among pediatric dermatologists and rheumatologists
British journal of dermatology. 2019 Jan ; 180:165-171
Comparing the importance of quality measurement themes in juvenile idiopathic inflammatory myositis between patients and families and healthcare professionals
Pediatric rheumatology online journal. 2018 Apr 19; 16:28
A Novel ELANE Mutation Associated with Inflammatory Arthritis, Defective NETosis, and Recurrent Parvoviral Infection
Arthritis & rheumatology. 2017 12 ; 69:2396-2401
Patient-provider discordance between global assessments of disease activity in rheumatoid arthritis: a comprehensive clinical evaluation
Arthritis research & therapy. 2017 09 26; 19:212