Pediatric Cardiology Research | NYU Langone Health

Division of Pediatric Cardiology Pediatric Cardiology Research

Pediatric Cardiology Research

Researchers in NYU Langone’s Division of Pediatric Cardiology are pioneers in three-dimensional advanced cardiac imaging and printing for cardiac congenital heart disease. Along with investigators in the Congenital Heart Program, the division works with this advanced technology for precise assessment of preintervention anatomy and surgery simulation. The dedicated Congenital Cardiovascular Care Unit provides clinical research opportunities to improve specialized treatment for children with cardiovascular disease.

The division collaborates with the New York City Office of Chief Medical Examiner to investigate genetic causes of sudden cardiac death. One of the aims is to understand the role of genetic mutations in sudden death in patients with no clinical history of cardiac abnormalities.

Division members are investigating how rare genetic mutations in cardiac genes produce arrhythmias. Another area of investigation is the development of a system that allows obstetricians to image fetal hearts at 12 to 16 weeks gestation, allowing for early consultation with fetal cardiac specialists. Quality-of-life research is also being conducted to determine the effects of multiple procedures and hospitalizations on patients with heart disease.

Every quarter, the division’s global team of researchers screens pediatric patients in Trinidad for cardiac conditions.

Recent Publications

Into Adulthood: Assessing Parental Perceptions and Concerns for Pediatric Heart Transplant Recipients Around the Transition Into Adult Care

Kaplow, Katya; Downey, Max C; Donnelly, Conor; Hillenburg, Joseph P; McQueen, Melissa; Anderson, Kathleen; Cousino, Melissa K; Varma, Manu; Singh, Rakesh K; Sidoti, Carolyn N; Massie, Allan B; Segev, Dorry L; Levan, Macey L

Pediatric transplantation. 2025 May ; 29:e70062

Pharmacokinetics and safety of clofazimine in children with rifampicin-resistant tuberculosis

Hughes, Jennifer A; Solans, Belén P; Garcia-Prats, Anthony J; Draper, Heather R; Schaaf, H Simon; Nielsen, James C; Nortier, Elri; Courtney, Ingrid; Palmer, Megan; van der Laan, Louvina; Savic, Radojka M; Hesseling, Anneke C

Journal of infectious diseases. 2025 Feb 11;

It's Getting Better All the Time: Decreased Cumulative Incidence of Waitlist Mortality in Pediatric Candidates Following 2018 Heart Allocation Policy Change

Donnelly, Conor; Motter, Jennifer D; Patel, Suhani S; Long, Jane J; Liyanage, Luckmini; Varma, Manu; Singh, Rakesh K; Segev, Dorry L; Massie, Allan B

Pediatric transplantation. 2025 Feb ; 29:e14904

Dual- Vs Single-Chamber Ventricular Pacing in Isolated Congenital Complete Atrioventricular Block in Infancy

Tan, Reina Bianca; Pierce, Kristyn A; Nielsen, James; Sanatani, Shubhayan; Fridman, Michael D; Stephenson, Elizabeth A; Rangu, Sowmith; Escudero, Carolina; Mah, Douglas; Hill, Allison; Kane, Austin M; Chaouki, A Sami; Ochoa Nunez, Luis; Kwok, Sit-Yee; Tsao, Sabrina; Kallas, Dania; Asaki, S Yukiko; Behere, Shashank; Dubin, Anne; Ratnasamy, Christopher; Robinson, Jeffrey A; Janson, Christopher M; Cecchin, Frank; Shah, Maully J

JACC: Clinical electrophysiology. 2025 Jan 31;

Age-Related Ventricular Tachycardia Substrate Characteristics for Repaired Tetralogy of Fallot Before Transcatheter Pulmonary Valve Placement

Moore, Jeremy P; Waldmann, Victor; Bessière, Francis; Babouri, Nawel; Cohen, Mitchell I; O'Leary, Edward T; Patel, Nimesh S; Nazer, Babak; Tan, Weiyi; Fish, Frank A; Dalal, Aarti S; Mariucci, Elisabetta; Tan, Reina B; Lloyd, Michael S; McLeod, Christopher J; Anderson, Charles C; Kanter, Ronald J; Johnson, Bryce V; Wang, Bo; Chang, Philip M; Newlon, Claire A; Su, Jonathan; Shannon, Kevin M; Bradfield, Jason S; Shivkumar, Kalyanam; Aboulhosn, Jamil A; Khairy, Paul

JACC: Clinical electrophysiology. 2025 Jan 08;

Deficits in Pre- and Post-transplant Functional, Motor, and Cognitive Deficits Associated With Graft Failure and Mortality in Pediatric Heart Transplant Recipients

Donnelly, Conor; Patel, Suhani S; Chiang, Teresa Po-Yu; Liyanage, Luckmini; Long, Jane J; Levan, Macey L; Varma, Manu R; Singh, Rakesh K; Segev, Dorry L; Massie, Allan B

Pediatric transplantation. 2024 Dec ; 28:e14874

Generation of an iPSC cell line (VANYHHi001-A) from a patient with cardiac arrythmias carrying CACNA1D, SCN5A, and DSP variants

Sleiman, Yvonne; Reisqs, Jean-Baptiste; Bianca Tan, Reina; Cecchin, Frank; Chahine, Mohamed; Boutjdir, Mohamed

Stem cell research. 2024 Nov 07; 81:103608

Cardiac manifestations and outcomes of COVID-19 vaccine-associated myocarditis in the young in the USA: longitudinal results from the Myocarditis After COVID Vaccination (MACiV) multicenter study

Jain, Supriya S; Anderson, Steven A; Steele, Jeremy M; Wilson, Hunter C; Muniz, Juan Carlos; Soslow, Jonathan H; Beroukhim, Rebecca S; Maksymiuk, Victoria; Jacquemyn, Xander; Frosch, Olivia H; Fonseca, Brian; Harahsheh, Ashraf S; Buddhe, Sujatha; Ashwath, Ravi C; Thacker, Deepika; Maskatia, Shiraz A; Misra, Nilanjana; Su, Jennifer A; Siddiqui, Saira; Vaiyani, Danish; Vaikom-House, Aswathy K; Campbell, M Jay; Klein, Jared; Huang, Sihong; Mathis, Christopher; Cornicelli, Matthew D; Sharma, Madhu; Nagaraju, Lakshmi; Ang, Jocelyn Y; Uppu, Santosh C; Ramachandran, Preeti; Patel, Jyoti K; Han, Frank; Mandell, Jason G; Akam-Venkata, Jyothsna; DiLorenzo, Michael P; Brumund, Michael; Bhatla, Puneet; Eshtehardi, Parham; Mehta, Karina; Glover, Katherine; Dove, Matthew L; Aldawsari, Khalifah A; Kumar, Anupam; Barfuss, Spencer B; Dorfman, Adam L; Minocha, Prashant K; Yonts, Alexandra B; Schauer, Jenna; Cheng, Andrew L; Robinson, Joshua D; Powell, Zachary; Srivastava, Shubhika; Chelliah, Anjali; Sanil, Yamuna; Hernandez, Lazaro E; Gaur, Lasya; Antonchak, Michael; Johnston, Marla; Reich, Jonathan D; Nair, Narayan; Drugge, Elizabeth D; Grosse-Wortmann, Lars

EClinicalMedicine. 2024 Oct ; 76:102809