Ion Channels & Immunity Program Faculty

Faculty in NYU Langone’s Ion Channels and Immunity Program lead interdisciplinary research projects to discern the role of ion channels and transporters in immunity.

Ion Channels and Immunity Program Leadership

Stefan Feske, MD, Program Director

Stefan Feske, MD
Dr. Feske is an internationally-recognized leader in the field of ion channels in immunity. The Feske Lab has published extensively on the mechanisms regulating the function of CRAC calcium channels formed by ORAI and STIM proteins and their role in immunity.

Dr. Feske is the scientific cofounder of CalciMedica, a biotechnology company that developed several drugs inhibiting CRAC channels that are in clinical trials for inflammatory diseases. In 2018, Dr. Feske organized the international Ion Channels and Immunity Symposium at NYU Langone that focused solely on the function of ion channels in immunity.

Dr. Feske is a member of the NYU Langone's Judith and Stewart Colton Center for Autoimmunity and Perlmutter Cancer Center. He leads the basic science and translational aspects of the program.

Learn more about Dr. Feske.

William A. Coetzee, PhD, Core Facility Director

William Coetzee, PhD
Dr. Coetzee is an established cellular electrophysiologist. His current research focus is in ion channel function, particularly as it relates to heart rhythm disorders, ischemic heart disease, and sudden death. His laboratory has used cellular electrophysiology techniques to study a variety of membrane currents in cardiac myocytes, skeletal muscle myotubes, coronary endothelial and smooth muscle cells, pancreatic β-cells, fibroblasts, immune cells, and transfected mammalian cells. Channels studied include KATP channels, the Na+/Ca2+ exchange current, the transient outward K+ current, inward rectifier K+ currents, the T- and L-type Ca2+ currents, the Na+ current, HCN4 currents, several voltage-gated K+ channels, stretch-activated chloride currents, outward rectifying chloride channels, mechanosensitive channels, Ca2+-activated K+ currents and two-pore K+ channels. Many of his studies were led in collaboration with other NYU Langone investigators.

Dr. Coetzee has more than 35 years of experience in cellular electrophysiology techniques and, as director of the Ion Channel and Immunity core facility, assists other investigators in planning experimental protocols and providing advice for data analysis.

Learn more about Dr. Coetzee.

Ion Channels and Immunity Program Affiliate Faculty

Iannis Aifantis, PhD
Chair, Department of Pathology

Rodrigo S. Lacruz, PhD
Associate Professor, Basic Science and Craniofacial Biology NYU College of Dentistry

George Miller, MD
H. Leon Pachter, MD Professor of Surgery, Department of Surgery

Greg E. Morley, PhD
Associate Professor, Department of Medicine

Benjamin G. Neel, MD, PhD
Director, Perlmutter Cancer Center

Timothy Niewold, MD
Director, Judith and Stewart Colton Center for Autoimmunity

Susan R. Schwab, PhD
Associate Professor, Department of Pathology

Edward Y. Skolnik, MD
Professor, Department of Medicine

Richard Tsien, PhD
Director, Neuroscience Institute