Immunology Research Program | NYU Langone Health

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Department of Pathology Research Immunology Research Program

Immunology Research Program

The Department of Pathology at NYU Langone is home to multiple labs studying all aspects of immunology. Our research teams lead basic studies of the immune system, as well as translational studies to identify novel clinical applications.

Immunology research in the Department of Pathology has an illustrious history featuring many exceptional scientists including Zoltan Ovary, who elucidated the role of IgE in anaphylaxis; Michael Heidelberger, whose pioneering work on pneumococcal polysaccharides led to the discovery that antibodies are proteins, earning him two Lasker awards; and Baruj Benacerraf, who won a Nobel Prize for his work on immune response genes and transplantation.

Faculty in the department’s immunology labs comprise the core faculty of NYU Langone’s Translational Immunology Center, Perlmutter Cancer Center’s Tumor Immunology Research Program, the Department of Pathology’s Ion Channels and Transporters in Immunity Research Program, and the Immunology and Inflammation PhD Training Program at the Vilcek Institute of Graduate Biomedical Sciences.

Immunology Research Areas

Many of our researchers study the basic mechanisms of immune responses. This includes work led by Stefan Feske, MD, in ion channel signaling in immune cells; Susan R. Schwab, PhD, in lymphocyte trafficking; Juan J. Lafaille, PhD, and Dan R. Littman, MD, PhD, in T-cell differentiation; Sergei B. Koralov, PhD, and Gregg Silverman, MD, in B-cell responses; and Shruti Naik, PhD, in immune cells in tissues such as the skin.

We also study mechanisms of normal immune system development from stem cells, and its subversion during leukemia, an area being investigated by Iannis Aifantis, PhD; Boris Reizis, PhD; and Jane Skok, PhD.

A major focus of our research is immune responses to pathogens, including mechanisms of interferon responses, studied by David E. Levy, PhD, and specific responses against HIV, studied by Miroslaw K. Gorny, MD, PhD, and Ralf Duerr, MD, PhD; and tuberculosis, studied by Suman Laal, PhD.

Finally, several faculty including Michelle Krogsgaard, PhD, Thales Y. Papagiannakopoulos, PhD, and Jun Wang, PhD, study immune responses to tumors and their application for cancer immunotherapy.

Immunology Research Facilities and Resources

Immunology research is facilitated by state-of-the-art core facilities including the Cytometry and Cell Sorting Laboratory headed by Peter A. Lopez, BS. Flow cytometry and other high-dimensional approaches to immune cell analysis are further developed at the Precision Immunology Laboratory. The Ion Laboratory, headed by William A. Coetzee, DSc, facilitates research in the area of ion channel and transporter function and ionic signaling in immune cells.

Immunology Research Faculty

Iannis Aifantis, PhD
Ralf Duerr, MD, PhD
Stefan Feske, MD
Miroslaw K. Gorny, MD, PhD
Sergei B. Koralov, PhD
Michelle Krogsgaard, PhD
Suman Laal, PhD
Juan J. Lafaille, PhD
David E. Levy, PhD
Dan R. Littman, MD, PhD
Peter A. Lopez, BS
Isabelle J. Marié, PhD
Shruti Naik, PhD
Victor Nussenzweig, MD, PhD
Zhiheng Pei, MD, PhD
Boris Reizis, PhD
Susan R. Schwab, PhD
Gregg Silverman, MD
Jane Skok, PhD
Jun Wang, PhD

Contact Us

For general inquiries about immunology research, please email Dr. Reizis, program director, at boris.reizis@nyulangone.org.