Division of Advanced Research Technologies | NYU Langone Health

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Scientific Cores & Shared Resources Division of Advanced Research Technologies

Division of Advanced Research Technologies

NYU Langone's Division of Advanced Research Technologies comprises core laboratories that are dedicated to facilitating basic, clinical, and translational research. Our scientists collaborate across academic disciplines and with partnering investigators from outside institutions and laboratories. 

Our team members recognize that the most complex problems in biomedical research require complex solutions—powerful technologies employed by experts who personify the ethos of collaboration as they conduct their studies with precision.

A diverse committee of faculty, core directors, and administrators provides strategic guidance, ensuring that our technology and practices enable our partners to perform more robust research.

What's New

Matthias Stadtfeld, PhD, and his team characterized the acquisition of developmental pluripotency in induced pluripotent stem cells (iPSCs), and found that nascent iPSCs exhibit a unique combination of properties that distinguishes them from canonical naive and primed pluripotency states. These observations close a gap in the understanding of induced pluripotency and provide an improved roadmap of cellular reprogramming with ramifications for the use of iPSCs in regenerative medicine. This work was supported by resources from our Rodent Genetic Engineering Laboratory, Cytometry and Cell Sorting Laboratory, and Genome Technology Center, and was co-authored by members of all three teams.

First Comprehensive Transcriptome Analysis of Human Aneuploidies

Aristotelis Tsirigos, PhD; Adriana Heguy, PhD; and colleagues have published the first comprehensive transcriptome analysis of human aneuploidies in preimplantation embryos. The study revealed significant transcriptional dysregulation in nonviable aneuploidies, suggesting that the majority of associated abnormalities occur very early in development. These findings may guide the development of new preimplantation genetic screening methods and shed new light on developmental abnormalities. This important work was supported by the Genome Technology Center, which provided expert library preparation and sequencing; the Applied Bioinformatics Laboratories, which carried out all data analysis and interpretation; and the High Performance Computing Core. The project was performed in collaboration with Frederick L. Licciardi, MD, at the NYU Langone Fertility Center, which delivered patient care, procured specimens, and provided financial support.

Neural Circuits of Walking Found in Fish

Jeremy Dasen, PhD, and David Schoppik, PhD, have published a high-profile paper in Cell on the discovery that the neural networks that underlie land walking can be found in fish. The groundbreaking work was facilitated by continued support from NYU Langone’s Genome Technology Center and Applied Bioinformatics Laboratories with data analysis and interpretation, and was co-authored by members of both teams.

Division of Advanced Research Technologies Administration

Genomics Research Expert, Doctor Adriana Heguy

Adriana Heguy, PhD
Assistant Dean, Division of Advanced Research Technologies
adriana.heguy@nyulangone.org

Division of Advanced Research Technologies Senior Director Sheenah Mische PhD

Sheenah Mische, PhD
Senior Director, Division of Advanced Research Technologies
sheenah.mische@nyulangone.org

Division of Advanced Research Technologies Administrative Coordinator Susana Esquenazi BS

Susana Esquenazi, BS
Administrative Coordinator, Division of Advanced Research Technologies
susana.esquenazi@nyulangone.org

Program Coordinator Kristine Lluveras

Kristine Lluveras, BA
’Omics Program Coordinator, Division of Advanced Research Technologies
kristine.lluveras@nyulangone.org

Tom Winner

Tom Winner, MBA
Director, Finance and Administration, Office of Science and Research
thomas.winner@nyulangone.org

Division of Advanced Research Technologies Advisory Committee

Jef Boeke, PhD
Professor, Department of Biochemistry and Molecular Pharmacology
Director, Institute for Systems Genetics

Bruce Cronstein, MD
The Dr. Paul R. Esserman Professor of Medicine, Department of Medicine
Professor, Department of Biochemistry and Molecular Pharmacology and Department of Pathology
Director, Program in Collaborative Research, Division of Translational Medicine, and Clinical and Translational Science Institute

Glenn Fishman, MD
The William Goldring Professor of Medicine, Department of Medicine
Professor, Department of Biochemistry and Molecular Pharmacology and Department of Neuroscience and Physiology
Vice Chair, Research, Department of Medicine
Director, Leon H. Charney Division of Cardiology

Ruth Lehmann, PhD
The Laura and Isaac Perlmutter Professor of Cell Biology and Chair, Department of Cell Biology
Director, Skirball Institute of Biomolecular Medicine
Director, Kimmel Center for Stem Cell Biology

Benjamin Neel, MD, PhD
Professor, Department of Medicine 
Director, Laura and Isaac Perlmutter Cancer Center

Richard Tsien, DPhil
The Druckenmiller Professor of Neuroscience and Chair, Department of Neuroscience and Physiology
Professor, Department of Neurology
Director, Neuroscience Institute

Itai Yanai, PhD
Professor, Department of Biochemistry and Molecular Pharmacology
Director, Institute for Computational Medicine